CEACAM5

From Wikipedia, the free encyclopedia


Carcinoembryonic antigen-related cell adhesion molecule 5
PDB rendering based on 1e07.
Available structures: 1e07
Identifiers
Symbol(s) CEACAM5; CD66e; CEA; DKFZp781M2392
External IDs OMIM: 114890
Orthologs
Human Mouse
Entrez 1048 n/a
Ensembl ENSG00000105388 n/a
Uniprot P06731 n/a
Refseq NM_004363 (mRNA)
NP_004354 (protein)		 n/a (mRNA)
n/a (protein)
Location Chr 19: 46.9 - 46.92 Mb n/a
Pubmed search [1] n/a

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (Cluster of Differentiation 66e), is a human gene.[1]


Contents

[edit] See also

[edit] References

  1. ^ Entrez Gene: CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5.

[edit] Further reading

  • Willcocks TC, Craig IW (1991). "Characterization of the genomic organization of human carcinoembryonic antigen (CEA): comparison with other family members and sequence analysis of 5' controlling region.". Genomics 8 (3): 492–500. PMID 2286372. 
  • Barnett T, Zimmermann W (1990). "Workshop report: proposed nomenclature for the carcinoembryonic antigen (CEA) gene family.". Tumour Biol. 11 (1-2): 59–63. PMID 2309067. 
  • Schrewe H, Thompson J, Bona M, et al. (1990). "Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression.". Mol. Cell. Biol. 10 (6): 2738–48. PMID 2342461. 
  • Kamarck ME, Elting JJ, Hart JT, et al. (1987). "Carcinoembryonic antigen family: expression in a mouse L-cell transfectant and characterization of a partial cDNA in bacteriophage lambda gt11.". Proc. Natl. Acad. Sci. U.S.A. 84 (15): 5350–4. PMID 2955415. 
  • Zimmermann W, Ortlieb B, Friedrich R, von Kleist S (1987). "Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure.". Proc. Natl. Acad. Sci. U.S.A. 84 (9): 2960–4. PMID 3033671. 
  • Barnett T, Goebel SJ, Nothdurft MA, Elting JJ (1989). "Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains.". Genomics 3 (1): 59–66. PMID 3220478. 
  • Zimmermann W, Weber B, Ortlieb B, et al. (1988). "Chromosomal localization of the carcinoembryonic antigen gene family and differential expression in various tumors.". Cancer Res. 48 (9): 2550–4. PMID 3356015. 
  • Beauchemin N, Benchimol S, Cournoyer D, et al. (1987). "Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen.". Mol. Cell. Biol. 7 (9): 3221–30. PMID 3670312. 
  • Oikawa S, Nakazato H, Kosaki G (1987). "Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence.". Biochem. Biophys. Res. Commun. 142 (2): 511–8. PMID 3814146. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Hart SP, Ross JA, Ross K, et al. (2000). "Molecular characterization of the surface of apoptotic neutrophils: implications for functional downregulation and recognition by phagocytes.". Cell Death Differ. 7 (5): 493–503. doi:10.1038/sj.cdd.4400680. PMID 10800083. 
  • Guignot J, Peiffer I, Bernet-Camard MF, et al. (2000). "Recruitment of CD55 and CD66e brush border-associated glycosylphosphatidylinositol-anchored proteins by members of the Afa/Dr diffusely adhering family of Escherichia coli that infect the human polarized intestinal Caco-2/TC7 cells.". Infect. Immun. 68 (6): 3554–63. PMID 10816511. 
  • Boehm MK, Perkins SJ (2000). "Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23.". FEBS Lett. 475 (1): 11–6. PMID 10854848. 
  • Screaton RA, DeMarte L, Dráber P, Stanners CP (2000). "The specificity for the differentiation blocking activity of carcinoembryonic antigen resides in its glycophosphatidyl-inositol anchor.". J. Cell Biol. 150 (3): 613–26. PMID 10931872. 
  • Bajenova OV, Zimmer R, Stolper E, et al. (2001). "Heterogeneous RNA-binding protein M4 is a receptor for carcinoembryonic antigen in Kupffer cells.". J. Biol. Chem. 276 (33): 31067–73. doi:10.1074/jbc.M104093200. PMID 11406629. 
  • Wirth T, Soeth E, Czubayko F, Juhl H (2002). "Inhibition of endogenous carcinoembryonic antigen (CEA) increases the apoptotic rate of colon cancer cells and inhibits metastatic tumor growth.". Clin. Exp. Metastasis 19 (2): 155–60. PMID 11964079. 
  • Louhimo J, Carpelan-Holmström M, Alfthan H, et al. (2002). "Serum HCG beta, CA 72-4 and CEA are independent prognostic factors in colorectal cancer.". Int. J. Cancer 101 (6): 545–8. doi:10.1002/ijc.90009. PMID 12237895. 
  • Hampton R, Walker M, Marshall J, Juhl H (2002). "Differential expression of carcinoembryonic antigen (CEA) splice variants in whole blood of colon cancer patients and healthy volunteers: implication for the detection of circulating colon cancer cells.". Oncogene 21 (51): 7817–23. doi:10.1038/sj.onc.1205906. PMID 12420218. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 

[edit] External links

 This membrane protein-related article is a stub. You can help Wikipedia by expanding it.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

v • d • e
Proteins: clusters of differentiation (see also list of human clusters of differentiation)
1-50
CD1 (a-c, 1A, 1D, 1E) - CD2 - CD3 (γ, δ, ε) - CD4 - CD5 - CD6 - CD7 - CD8 (a) - CD9 - CD10 - CD11 (a, b, c) - CD13 - CD14 - CD15 - CD16 (A, B) - CD18 - CD19 - CD20 - CD21 - CD22 - CD23 - CD24 - CD25 - CD26 - CD27 - CD28 - CD29 - CD30 - CD31 - CD32 (A, B) - CD33 - CD34 - CD35 - CD36 - CD37 - CD38 - CD39 - CD40 - CD41- CD42 (a, b, c, d) - CD43 - CD44 - CD45 - CD46 - CD47 - CD48 - CD49 (a, b, c, d, e, f) - CD50
51-100
CD51 - CD52 - CD53 - CD54 - CD55 - CD56 - CD57- CD58 - CD59 - CD61 - CD62 (E, L, P) - CD63 - CD64 - CD66 (a, b, c, d, e, f) - CD68 - CD69 - CD70 - CD71 - CD72 - CD73 - CD74 - CD79 (a, b) - CD80 - CD81 - CD82 - CD83 - CD84 - CD85 (a, d, e, h, j, k) - CD86 - CD87 - CD88 - CD89 - CD90 - CD91- CD92 - CD93 - CD94 - CD95 - CD97 - CD98 - CD99 - CD100
101-150
CD101 - CD102 - CD103 - CD104 - CD105 - CD106 - CD107 (a, b) - CD108 - CD109 - CD110 - CD111 - CD112 - CD113 - CD114 - CD115 - CD116 - CD117 - CD118 - CD119 - CD120 (a, b) - CD121 (a, b) - CD122 - CD123 - CD124 - CD125 - CD126 - CD127 - CD129 - CD130 - CD131 - CD132 - CD133 - CD134 - CD135 - CD136 - CD137 - CD138 - CD140b - CD141 - CD142 - CD143 - CD144 - CD146 - CD147 - CD148 - CD150
151-200
CD151 - CD152 - CD153 - CD154 - CD155 - CD156 (a, b, c) - CD157 - CD158 (a, d, e, i, k) - CD159 (a, c) - CD160 - CD161 - CD162 - CD163 - CD164 - CD166 - CD167 (a, b) - CD168 - CD169 - CD170 - CD171 - CD172 (a, b, g) - CD174 - CD177 - CD178 - CD179 (a, b) - CD181 - CD182 - CD183 - CD184 - CD185 - CD186 - CD191 - CD192 - CD193 - CD194 - CD195 - CD196 - CD197 - CDw198 - CDw199 - CD200
201-250
CD201 - CD202b - CD204 - CD205 - CD206 - CD207 - CD208 - CD209 - CDw210 (a, b) - CD212 - CD213a (1, 2) - CD217 - CD218 (a, b) - CD220 - CD221 - CD222 - CD223 - CD224 - CD225 - CD226 - CD227 - CD228 - CD229 - CD230 - CD233 - CD234 - CD235 (a, b) - CD236 - CD238 - CD239 - CD240CE - CD241 - CD243 - CD244 - CD246 - CD247- CD248 - CD249
251-300
301-350