CD248

From Wikipedia, the free encyclopedia


CD248 molecule, endosialin
Identifiers
Symbol(s) CD248; CD164L1; MGC119478; MGC119479; TEM1
External IDs OMIM: 606064 MGI1917695 HomoloGene10699
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 57124 70445
Ensembl ENSG00000174807 ENSMUSG00000056481
Uniprot Q9HCU0 Q91V98
Refseq NM_020404 (mRNA)
NP_065137 (protein)
NM_054042 (mRNA)
NP_473383 (protein)
Location Chr 11: 65.84 - 65.84 Mb Chr 19: 5.07 - 5.07 Mb
Pubmed search [1] [2]

CD248 molecule, endosialin, also known as CD248, is a human gene.[1]


Contents

[edit] See also

[edit] References

[edit] Further reading

  • Rettig WJ, Garin-Chesa P, Healey JH, et al. (1992). "Identification of endosialin, a cell surface glycoprotein of vascular endothelial cells in human cancer.". Proc. Natl. Acad. Sci. U.S.A. 89 (22): 10832–6. PMID 1438285. 
  • St Croix B, Rago C, Velculescu V, et al. (2000). "Genes expressed in human tumor endothelium.". Science 289 (5482): 1197–202. PMID 10947988. 
  • Christian S, Ahorn H, Koehler A, et al. (2001). "Molecular cloning and characterization of endosialin, a C-type lectin-like cell surface receptor of tumor endothelium.". J. Biol. Chem. 276 (10): 7408–14. doi:10.1074/jbc.M009604200. PMID 11084048. 
  • Opavsky R, Haviernik P, Jurkovicova D, et al. (2001). "Molecular characterization of the mouse Tem1/endosialin gene regulated by cell density in vitro and expressed in normal tissues in vivo.". J. Biol. Chem. 276 (42): 38795–807. doi:10.1074/jbc.M105241200. PMID 11489895. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Brady J, Neal J, Sadakar N, Gasque P (2005). "Human endosialin (tumor endothelial marker 1) is abundantly expressed in highly malignant and invasive brain tumors.". J. Neuropathol. Exp. Neurol. 63 (12): 1274–83. PMID 15624764. 
  • MacFadyen JR, Haworth O, Roberston D, et al. (2005). "Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium.". FEBS Lett. 579 (12): 2569–75. doi:10.1016/j.febslet.2005.03.071. PMID 15862292. 
  • Dolznig H, Schweifer N, Puri C, et al. (2006). "Characterization of cancer stroma markers: in silico analysis of an mRNA expression database for fibroblast activation protein and endosialin.". Cancer Immun. 5: 10. PMID 16076089. 
  • Tomkowicz B, Rybinski K, Foley B, et al. (2008). "Interaction of endosialin/TEM1 with extracellular matrix proteins mediates cell adhesion and migration.". Proc. Natl. Acad. Sci. U.S.A. 104 (46): 17965–70. doi:10.1073/pnas.0705647104. PMID 17986615. 

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