CD248
From Wikipedia, the free encyclopedia
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CD248 molecule, endosialin
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| Identifiers | ||||||||||||||
| Symbol(s) | CD248; CD164L1; MGC119478; MGC119479; TEM1 | |||||||||||||
| External IDs | OMIM: 606064 MGI: 1917695 HomoloGene: 10699 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 57124 | 70445 | ||||||||||||
| Ensembl | ENSG00000174807 | ENSMUSG00000056481 | ||||||||||||
| Uniprot | Q9HCU0 | Q91V98 | ||||||||||||
| Refseq | NM_020404 (mRNA) NP_065137 (protein) |
NM_054042 (mRNA) NP_473383 (protein) |
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| Location | Chr 11: 65.84 - 65.84 Mb | Chr 19: 5.07 - 5.07 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
CD248 molecule, endosialin, also known as CD248, is a human gene.[1]
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[edit] See also
[edit] References
[edit] Further reading
- Rettig WJ, Garin-Chesa P, Healey JH, et al. (1992). "Identification of endosialin, a cell surface glycoprotein of vascular endothelial cells in human cancer.". Proc. Natl. Acad. Sci. U.S.A. 89 (22): 10832–6. PMID 1438285.
- St Croix B, Rago C, Velculescu V, et al. (2000). "Genes expressed in human tumor endothelium.". Science 289 (5482): 1197–202. PMID 10947988.
- Christian S, Ahorn H, Koehler A, et al. (2001). "Molecular cloning and characterization of endosialin, a C-type lectin-like cell surface receptor of tumor endothelium.". J. Biol. Chem. 276 (10): 7408–14. doi:. PMID 11084048.
- Opavsky R, Haviernik P, Jurkovicova D, et al. (2001). "Molecular characterization of the mouse Tem1/endosialin gene regulated by cell density in vitro and expressed in normal tissues in vivo.". J. Biol. Chem. 276 (42): 38795–807. doi:. PMID 11489895.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:. PMID 15489334.
- Brady J, Neal J, Sadakar N, Gasque P (2005). "Human endosialin (tumor endothelial marker 1) is abundantly expressed in highly malignant and invasive brain tumors.". J. Neuropathol. Exp. Neurol. 63 (12): 1274–83. PMID 15624764.
- MacFadyen JR, Haworth O, Roberston D, et al. (2005). "Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium.". FEBS Lett. 579 (12): 2569–75. doi:. PMID 15862292.
- Dolznig H, Schweifer N, Puri C, et al. (2006). "Characterization of cancer stroma markers: in silico analysis of an mRNA expression database for fibroblast activation protein and endosialin.". Cancer Immun. 5: 10. PMID 16076089.
- Tomkowicz B, Rybinski K, Foley B, et al. (2008). "Interaction of endosialin/TEM1 with extracellular matrix proteins mediates cell adhesion and migration.". Proc. Natl. Acad. Sci. U.S.A. 104 (46): 17965–70. doi:. PMID 17986615.

