BST2
From Wikipedia, the free encyclopedia
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Bone marrow stromal cell antigen 2
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| Identifiers | ||||||||||||||
| Symbol(s) | BST2; CD317 | |||||||||||||
| External IDs | OMIM: 600534 MGI: 1916800 HomoloGene: 48277 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 684 | 69550 | ||||||||||||
| Ensembl | ENSG00000130303 | ENSMUSG00000046718 | ||||||||||||
| Uniprot | Q10589 | Q8R2Q8 | ||||||||||||
| Refseq | NM_004335 (mRNA) NP_004326 (protein) |
NM_198095 (mRNA) NP_932763 (protein) |
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| Location | Chr 19: 17.37 - 17.38 Mb | Chr 8: 74.46 - 74.47 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Bone marrow stromal cell antigen 2, also known as BST2, is a human gene.[1] BST2 has also been designated as CD317 (cluster of differentiation 317).
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis.[1]
[edit] References
[edit] Further reading
- Ishikawa J, Kaisho T, Tomizawa H, et al. (1995). "Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth.". Genomics 26 (3): 527-34. PMID 7607676.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
- Furuya Y, Takasawa S, Yonekura H, et al. (1996). "Cloning of a cDNA encoding rat bone marrow stromal cell antigen 1 (BST-1) from the islets of Langerhans.". Gene 165 (2): 329-30. PMID 8522202.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
- Ohtomo T, Sugamata Y, Ozaki Y, et al. (1999). "Molecular cloning and characterization of a surface antigen preferentially overexpressed on multiple myeloma cells.". Biochem. Biophys. Res. Commun. 258 (3): 583-91. doi:. PMID 10329429.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:. PMID 12477932.
- Matsuda A, Suzuki Y, Honda G, et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.". Oncogene 22 (21): 3307-18. doi:. PMID 12761501.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:. PMID 15489334.
- Vidal-Laliena M, Romero X, March S, et al. (2006). "Characterization of antibodies submitted to the B cell section of the 8th Human Leukocyte Differentiation Antigens Workshop by flow cytometry and immunohistochemistry.". Cell. Immunol. 236 (1-2): 6-16. doi:. PMID 16157322.
- Elortza F, Mohammed S, Bunkenborg J, et al. (2006). "Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment.". J. Proteome Res. 5 (4): 935-43. doi:. PMID 16602701.
[edit] External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.

