BST2

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Bone marrow stromal cell antigen 2
Identifiers
Symbol(s) BST2; CD317
External IDs OMIM: 600534 MGI1916800 HomoloGene48277
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 684 69550
Ensembl ENSG00000130303 ENSMUSG00000046718
Uniprot Q10589 Q8R2Q8
Refseq NM_004335 (mRNA)
NP_004326 (protein)
NM_198095 (mRNA)
NP_932763 (protein)
Location Chr 19: 17.37 - 17.38 Mb Chr 8: 74.46 - 74.47 Mb
Pubmed search [1] [2]

Bone marrow stromal cell antigen 2, also known as BST2, is a human gene.[1] BST2 has also been designated as CD317 (cluster of differentiation 317).

Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis.[1]

[edit] References

[edit] Further reading

  • Ishikawa J, Kaisho T, Tomizawa H, et al. (1995). "Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth.". Genomics 26 (3): 527-34. PMID 7607676. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298. 
  • Furuya Y, Takasawa S, Yonekura H, et al. (1996). "Cloning of a cDNA encoding rat bone marrow stromal cell antigen 1 (BST-1) from the islets of Langerhans.". Gene 165 (2): 329-30. PMID 8522202. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149. 
  • Ohtomo T, Sugamata Y, Ozaki Y, et al. (1999). "Molecular cloning and characterization of a surface antigen preferentially overexpressed on multiple myeloma cells.". Biochem. Biophys. Res. Commun. 258 (3): 583-91. doi:10.1006/bbrc.1999.0683. PMID 10329429. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Matsuda A, Suzuki Y, Honda G, et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.". Oncogene 22 (21): 3307-18. doi:10.1038/sj.onc.1206406. PMID 12761501. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Vidal-Laliena M, Romero X, March S, et al. (2006). "Characterization of antibodies submitted to the B cell section of the 8th Human Leukocyte Differentiation Antigens Workshop by flow cytometry and immunohistochemistry.". Cell. Immunol. 236 (1-2): 6-16. doi:10.1016/j.cellimm.2005.08.002. PMID 16157322. 
  • Elortza F, Mohammed S, Bunkenborg J, et al. (2006). "Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment.". J. Proteome Res. 5 (4): 935-43. doi:10.1021/pr050419u. PMID 16602701. 

[edit] External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.