CD163
From Wikipedia, the free encyclopedia
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CD163 molecule
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| Identifiers | ||||||||||||||
| Symbol(s) | CD163; M130; MM130 | |||||||||||||
| External IDs | OMIM: 605545 MGI: 2135946 HomoloGene: 3131 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 9332 | 93671 | ||||||||||||
| Ensembl | ENSG00000177575 | ENSMUSG00000008845 | ||||||||||||
| Uniprot | Q86VB7 | Q2VLH6 | ||||||||||||
| Refseq | NM_004244 (mRNA) NP_004235 (protein) |
XM_981067 (mRNA) XP_986161 (protein) |
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| Location | Chr 12: 7.52 - 7.55 Mb | Chr 6: 124.27 - 124.3 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
CD163 (Cluster of Differentiation 163) is a human protein encoded by the CD163 gene.[1]
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[edit] See also
[edit] References
[edit] Further reading
- Graversen JH, Madsen M, Moestrup SK (2002). "CD163: a signal receptor scavenging haptoglobin-hemoglobin complexes from plasma.". Int. J. Biochem. Cell Biol. 34 (4): 309-14. PMID 11854028.
- Madsen M, Graversen JH, Moestrup SK (2002). "Haptoglobin and CD163: captor and receptor gating hemoglobin to macrophage lysosomes.". Redox Rep. 6 (6): 386-8. PMID 11865982.
- Moestrup SK, Møller HJ (2005). "CD163: a regulated hemoglobin scavenger receptor with a role in the anti-inflammatory response.". Ann. Med. 36 (5): 347-54. PMID 15478309.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
- Law SK, Micklem KJ, Shaw JM, et al. (1993). "A new macrophage differentiation antigen which is a member of the scavenger receptor superfamily.". Eur. J. Immunol. 23 (9): 2320-5. PMID 8370408.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
- Droste A, Sorg C, Högger P (1999). "Shedding of CD163, a novel regulatory mechanism for a member of the scavenger receptor cysteine-rich family.". Biochem. Biophys. Res. Commun. 256 (1): 110-3. doi:. PMID 10066432.
- Ritter M, Buechler C, Langmann T, Schmitz G (1999). "Genomic organization and chromosomal localization of the human CD163 (M130) gene: a member of the scavenger receptor cysteine-rich superfamily.". Biochem. Biophys. Res. Commun. 260 (2): 466-74. doi:. PMID 10403791.
- Van den Heuvel MM, Tensen CP, van As JH, et al. (1999). "Regulation of CD 163 on human macrophages: cross-linking of CD163 induces signaling and activation.". J. Leukoc. Biol. 66 (5): 858-66. PMID 10577520.
- Buechler C, Ritter M, Orsó E, et al. (2000). "Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli.". J. Leukoc. Biol. 67 (1): 97-103. PMID 10648003.
- Stover CM, Schleypen J, Grønlund J, et al. (2001). "Assignment of CD163B, the gene encoding M160, a novel scavenger receptor, to human chromosome 12p13.3 by in situ hybridization and somatic cell hybrid analysis.". Cytogenet. Cell Genet. 90 (3-4): 246-7. PMID 11124526.
- Kristiansen M, Graversen JH, Jacobsen C, et al. (2001). "Identification of the haemoglobin scavenger receptor.". Nature 409 (6817): 198-201. doi:. PMID 11196644.
- Ritter M, Buechler C, Kapinsky M, Schmitz G (2001). "Interaction of CD163 with the regulatory subunit of casein kinase II (CKII) and dependence of CD163 signaling on CKII and protein kinase C.". Eur. J. Immunol. 31 (4): 999-1009. PMID 11298324.
- Sulahian TH, Hintz KA, Wardwell K, Guyre PM (2001). "Development of an ELISA to measure soluble CD163 in biological fluids.". J. Immunol. Methods 252 (1-2): 25-31. PMID 11334962.
- Högger P, Sorg C (2001). "Soluble CD163 inhibits phorbol ester-induced lymphocyte proliferation.". Biochem. Biophys. Res. Commun. 288 (4): 841-3. doi:. PMID 11688984.
- Fonseca JE, Edwards JC, Blades S, Goulding NJ (2002). "Macrophage subpopulations in rheumatoid synovium: reduced CD163 expression in CD4+ T lymphocyte-rich microenvironments.". Arthritis Rheum. 46 (5): 1210-6. doi:. PMID 12115225.
- Frings W, Dreier J, Sorg C (2002). "Only the soluble form of the scavenger receptor CD163 acts inhibitory on phorbol ester-activated T-lymphocytes, whereas membrane-bound protein has no effect.". FEBS Lett. 526 (1-3): 93-6. PMID 12208511.
- Matsushita N, Kashiwagi M, Wait R, et al. (2002). "Elevated levels of soluble CD163 in sera and fluids from rheumatoid arthritis patients and inhibition of the shedding of CD163 by TIMP-3.". Clin. Exp. Immunol. 130 (1): 156-61. PMID 12296867.
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