CD99

From Wikipedia, the free encyclopedia


CD99 molecule
Identifiers
Symbol(s) CD99; MIC2; MIC2X; MIC2Y
External IDs OMIM: 313470 HomoloGene48107
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 4267 n/a
Ensembl ENSG00000002586 n/a
Uniprot P14209 n/a
Refseq NM_002414 (mRNA)
NP_002405 (protein)
n/a (mRNA)
n/a (protein)
Location Chr X: 2.62 - 2.67 Mb n/a
Pubmed search [1] n/a

CD99 (Cluster of Differentiation 99) is a human protein encoded by the CD99 gene.[1]


Contents

[edit] See also

[edit] References

[edit] Further reading

  • Goodfellow PJ, Mondello C, Darling SM, et al. (1988). "Absence of methylation of a CpG-rich region at the 5' end of the MIC2 gene on the active X, the inactive X, and the Y chromosome.". Proc. Natl. Acad. Sci. U.S.A. 85 (15): 5605–9. PMID 2456574. 
  • Banting GS, Pym B, Darling SM, Goodfellow PN (1989). "The MIC2 gene product: epitope mapping and structural prediction analysis define an integral membrane protein.". Mol. Immunol. 26 (2): 181–8. PMID 2465491. 
  • Gelin C, Aubrit F, Phalipon A, et al. (1989). "The E2 antigen, a 32 kd glycoprotein involved in T-cell adhesion processes, is the MIC2 gene product.". EMBO J. 8 (11): 3253–9. PMID 2479542. 
  • Darling SM, Goodfellow PJ, Pym B, et al. (1987). "Molecular genetics of MIC2: a gene shared by the human X and Y chromosomes.". Cold Spring Harb. Symp. Quant. Biol. 51 Pt 1: 205–12. PMID 3472717. 
  • Buckle V, Mondello C, Darling S, et al. (1985). "Homologous expressed genes in the human sex chromosome pairing region.". Nature 317 (6039): 739–41. PMID 4058580. 
  • Dworzak MN, Fritsch G, Buchinger P, et al. (1994). "Flow cytometric assessment of human MIC2 expression in bone marrow, thymus, and peripheral blood.". Blood 83 (2): 415–25. PMID 7506950. 
  • Choi EY, Park WS, Jung KC, et al. (1998). "Engagement of CD99 induces up-regulation of TCR and MHC class I and II molecules on the surface of human thymocytes.". J. Immunol. 161 (2): 749–54. PMID 9670951. 
  • Gordon MD, Corless C, Renshaw AA, Beckstead J (1998). "CD99, keratin, and vimentin staining of sex cord-stromal tumors, normal ovary, and testis.". Mod. Pathol. 11 (8): 769–73. PMID 9720506. 
  • Fouchet C, Gane P, Cartron JP, Lopez C (2000). "Quantitative analysis of XG blood group and CD99 antigens on human red cells.". Immunogenetics 51 (8-9): 688–94. PMID 10941840. 
  • Jung KC, Park WS, Bae YM, et al. (2003). "Immunoreactivity of CD99 in stomach cancer.". J. Korean Med. Sci. 17 (4): 483–9. PMID 12172043. 
  • Lee HJ, Kim E, Jee B, et al. (2003). "Functional involvement of src and focal adhesion kinase in a CD99 splice variant-induced motility of human breast cancer cells.". Exp. Mol. Med. 34 (3): 177–83. PMID 12216109. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Veräjäkorva E, Laato M, Pöllänen P (2003). "CD 99 and CD 106 (VCAM-1) in human testis.". Asian J. Androl. 4 (4): 243–8. PMID 12508122. 
  • Gil MC, Lee MH, Seo JI, et al. (2004). "Characterization and epitope mapping of two monoclonal antibodies against human CD99.". Exp. Mol. Med. 34 (6): 411–8. PMID 12526082. 
  • Yoon SS, Jung KI, Choi YL, et al. (2003). "Engagement of CD99 triggers the exocytic transport of ganglioside GM1 and the reorganization of actin cytoskeleton.". FEBS Lett. 540 (1-3): 217–22. PMID 12681511. 
  • Kim MK, Choi YL, Kim MK, et al. (2003). "MHC class II engagement inhibits CD99-induced apoptosis and up-regulation of T cell receptor and MHC molecules in human thymocytes and T cell line.". FEBS Lett. 546 (2-3): 379–84. PMID 12832073. 
  • Jung KC, Kim NH, Park WS, et al. (2003). "The CD99 signal enhances Fas-mediated apoptosis in the human leukemic cell line, Jurkat.". FEBS Lett. 554 (3): 478–84. PMID 14623115. 
  • Lee EJ, Lee HG, Park SH, et al. (2004). "CD99 type II is a determining factor for the differentiation of primitive neuroectodermal cells.". Exp. Mol. Med. 35 (5): 438–47. PMID 14646598. 
  • Mahmood MN, Salama ME, Chaffins M, et al. (2004). "Solitary sclerotic fibroma of skin: a possible link with pleomorphic fibroma with immunophenotypic expression for O13 (CD99) and CD34.". J. Cutan. Pathol. 30 (10): 631–6. PMID 14744088. 
  • Cerisano V, Aalto Y, Perdichizzi S, et al. (2004). "Molecular mechanisms of CD99-induced caspase-independent cell death and cell-cell adhesion in Ewing's sarcoma cells: actin and zyxin as key intracellular mediators.". Oncogene 23 (33): 5664–74. doi:10.1038/sj.onc.1207741. PMID 15184883. 

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