CD300A

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CD300a molecule
Identifiers
Symbol(s) CD300A; CMRF-35-H9; CMRF-35H; CMRF35H; CMRF35H9; IGSF12; IRC1; IRC2; IRp60
External IDs OMIM: 606790 MGI: 2443411 HomoloGene: 48514
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 11314 217303
Ensembl ENSG00000167851 ENSMUSG00000034652
Uniprot Q9UGN4 n/a
Refseq NM_007261 (mRNA)
NP_009192 (protein)		 NM_170758 (mRNA)
NP_739564 (protein)
Location Chr 17: 69.97 - 69.99 Mb Chr 11: 114.71 - 114.72 Mb
Pubmed search [1] [2]

CD300A (Cluster of Differentiation 300A) is a human gene.[1]

The CMRF35 antigen (CMRF35A; MIM 606786), which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes. CMRF35H is recognized by the same antibody and is distinct from CMRF35 (Green et al., 1998).[supplied by OMIM][1]

Contents

[edit] References

  1. ^ a b Entrez Gene: CD300A CD300a molecule.

[edit] See also

[edit] Further reading

  • Clark GJ, Fitzpatrick S, Kuo B, et al. (2003). "CMRF-35A, CMRF-35H: potential new CD.". J. Biol. Regul. Homeost. Agents 16 (3): 233–5. PMID 12456026. 
  • Alvarez Y, Tang X, Coligan JE, Borrego F (2007). "The CD300a (IRp60) inhibitory receptor is rapidly up-regulated on human neutrophils in response to inflammatory stimuli and modulates CD32a (FcgammaRIIa) mediated signaling.". Mol. Immunol. 45 (1): 253–8. doi:10.1016/j.molimm.2007.05.006. PMID 17588661. 
  • Bachelet I, Munitz A, Moretta A, et al. (2006). "The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells.". J. Immunol. 175 (12): 7989–95. PMID 16339535. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Clark GJ, Green BJ, Hart DN (2000). "The CMRF-35H gene structure predicts for an independently expressed member of an ITIM/ITAM pair of molecules localized to human chromosome 17.". Tissue Antigens 55 (2): 101–9. PMID 10746781. 
  • Cantoni C, Bottino C, Augugliaro R, et al. (1999). "Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells.". Eur. J. Immunol. 29 (10): 3148–59. PMID 10540326. 
  • Green BJ, Clark GJ, Hart DN (1998). "The CMRF-35 mAb recognizes a second leukocyte membrane molecule with a domain similar to the poly Ig receptor.". Int. Immunol. 10 (7): 891–9. PMID 9701027. 
  • Jackson DG, Hart DN, Starling G, Bell JI (1992). "Molecular cloning of a novel member of the immunoglobulin gene superfamily homologous to the polymeric immunoglobulin receptor.". Eur. J. Immunol. 22 (5): 1157–63. PMID 1349532. 

[edit] External links

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v • d • e
Proteins: clusters of differentiation (see also list of human clusters of differentiation)
1-50
CD1 (a-c, 1A, 1D, 1E) - CD2 - CD3 (γ, δ, ε) - CD4 - CD5 - CD6 - CD7 - CD8 (a) - CD9 - CD10 - CD11 (a, b, c) - CD13 - CD14 - CD15 - CD16 (A, B) - CD18 - CD19 - CD20 - CD21 - CD22 - CD23 - CD24 - CD25 - CD26 - CD27 - CD28 - CD29 - CD30 - CD31 - CD32 (A, B) - CD33 - CD34 - CD35 - CD36 - CD37 - CD38 - CD39 - CD40 - CD41- CD42 (a, b, c, d) - CD43 - CD44 - CD45 - CD46 - CD47 - CD48 - CD49 (a, b, c, d, e, f) - CD50
51-100
CD51 - CD52 - CD53 - CD54 - CD55 - CD56 - CD57- CD58 - CD59 - CD61 - CD62 (E, L, P) - CD63 - CD64 - CD66 (a, b, c, d, e, f) - CD68 - CD69 - CD70 - CD71 - CD72 - CD73 - CD74 - CD79 (a, b) - CD80 - CD81 - CD82 - CD83 - CD84 - CD85 (a, d, e, h, j, k) - CD86 - CD87 - CD88 - CD89 - CD90 - CD91- CD92 - CD93 - CD94 - CD95 - CD97 - CD98 - CD99 - CD100
101-150
CD101 - CD102 - CD103 - CD104 - CD105 - CD106 - CD107 (a, b) - CD108 - CD109 - CD110 - CD111 - CD112 - CD113 - CD114 - CD115 - CD116 - CD117 - CD118 - CD119 - CD120 (a, b) - CD121 (a, b) - CD122 - CD123 - CD124 - CD125 - CD126 - CD127 - CD129 - CD130 - CD131 - CD132 - CD133 - CD134 - CD135 - CD136 - CD137 - CD138 - CD140b - CD141 - CD142 - CD143 - CD144 - CD146 - CD147 - CD148 - CD150
151-200
CD151 - CD152 - CD153 - CD154 - CD155 - CD156 (a, b, c) - CD157 - CD158 (a, d, e, i, k) - CD159 (a, c) - CD160 - CD161 - CD162 - CD163 - CD164 - CD166 - CD167 (a, b) - CD168 - CD169 - CD170 - CD171 - CD172 (a, b, g) - CD174 - CD177 - CD178 - CD179 (a, b) - CD181 - CD182 - CD183 - CD184 - CD185 - CD186 - CD191 - CD192 - CD193 - CD194 - CD195 - CD196 - CD197 - CDw198 - CDw199 - CD200
201-250
CD201 - CD202b - CD204 - CD205 - CD206 - CD207 - CD208 - CD209 - CDw210 (a, b) - CD212 - CD213a (1, 2) - CD217 - CD218 (a, b) - CD220 - CD221 - CD222 - CD223 - CD224 - CD225 - CD226 - CD227 - CD228 - CD229 - CD230 - CD233 - CD234 - CD235 (a, b) - CD236 - CD238 - CD239 - CD240CE - CD241 - CD243 - CD244 - CD246 - CD247- CD248 - CD249
251-300
301-350