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Transmembrane receptor: G protein-coupled receptors |
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| Class A: Rhodopsin like |
Acetylcholine ( M1, M2, M3, M4, M5) - Adrenergic ( α1 ( A, B, D), α2 ( A, B, C), β1, β2, β3) - Adrenomedullin - Anaphylatoxin ( C3a, C5a) - Angiotensin ( 1, 2) - Apelin - Bile acid - Bombesin ( BRS3, GRPR, NMBR) - Bradykinin ( B1, B2) - Cannabinoid ( CB1, CB2) - Chemokine - Cholecystokinin ( A, B) - Dopamine ( D1, D2, D3, D4, D5) - Eicosanoid ( CysLT ( 1, 2), LTB4 ( 1, 2), FPRL1, OXE, Prostaglandin (( DP ( 1, 2), EP ( 1, 2, 3, 4), PGF, Prostacyclin, Thromboxane) - EBI2 - Endothelin ( A, B) - Estrogen - Formyl peptide ( 1, L1, L2) - Free fatty acid ( 1, 2, 3, 4) - FSH - Galanin ( 1, 2, 3) - Gonadotropin-releasing hormone ( 1, 2) - GPR ( 1, 3, 4, 6, 12, 15, 17, 18, 19, 20, 21, 22, 23, 25, 26, 27, 31, 32, 33, 34, 35, 37, 39, 42, 44, 45, 50, 52, 55, 61, 62, 63, 65, 68, 75, 77, 78, 79, 82, 83, 84, 85, 87, 88, 92, 101, 103, 119, 120, 132, 135, 139, 141, 142, 146, 148, 149, 150, 151, 152, 153, 160, 161, 162, 171, 172, 173, 174, 176, 177, 182) - Ghrelin - Histamine ( H1, H2, H3, H4) - Kisspeptin - Luteinizing hormone/choriogonadotropin - Lysophospholipid ( 1, 2, 3, 4, 5, 6, 7, 8) - MAS ( 1, 1L, D, E, F, G, X1, X2, X3, X4) - Melanocortin ( 1, 2, 3, 4, 5) - MCHR ( 1, 2) - Melatonin ( 1A, 1B)- Motilin - neuromedin ( B, U ( 1, 2)) - Neuropeptide ( B/W ( 1, 2), FF ( 1, 2), S, Y ( 1, 2, 4, 5)) - Neurotensin ( 1, 2) - Opioid ( Delta, Kappa, Mu, Nociceptin, but not Sigma) - Olfactory - Opsin ( 3, 4, 5, 1LW, 1MW, 1SW, RGR, RRH) - Orexin ( 1, 2) - Oxytocin - Oxoglutarate - PAF - Prokineticin ( 1, 2) - Prolactin-releasing peptide - Protease-activated ( 1, 2, 3, 4) - Purinergics ( Adenosine ( A1, A2a, A2b, A3), P2Y, ( 1, 2, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14)) - Relaxin ( 1, 2, 3, 4) - Somatostatin ( 1, 2, 3, 4, 5) - Serotonin, all but 5-HT3 ( 5-HT1 ( A, B, D, E, F), 5-HT2 ( A, B, C), 5-HT ( 4, 5A, 6, 7)) - SREB - Succinate - TAAR ( 1, 2, 3, 5, 6, 8, 9) - Tachykinin ( 1, 2, 3) - Thyrotropin - Thyrotropin-releasing hormone - Urotensin-II - Vasopressin ( 1A, 1B, 2)
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| Class B: Secretin like |
Brain-specific angiogenesis inhibitor ( 1, 2, 3) - Cadherin ( 1, 2, 3) - Calcitonin - CD97 - Corticotropin-releasing hormone ( 1, 2) - EMR ( 1, 2, 3) - Glucagon ( GR, GIPR, GLP1R, GLP2R) - Growth hormone releasing hormone - PACAPR1- GPR ( 56, 64, 97, 98, 110, 111, 112, 113, 114, 115, 116, 123, 124, 125, 126, 128, 133, 143, 144, 157) - Latrophilin ( 1, 2, 3, ELTD1) - Parathyroid hormone ( 1, 2) - Secretin - Vasoactive intestinal peptide ( 1, 2)
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Class C: Metabotropic
glutamate / pheromone |
Calcium-sensing receptor - GABA B ( 1, 2) - Glutamate receptor ( Metabotropic glutamate ( 1, 2, 3, 4, 5, 6, 7, 8)) - GPRC6A - GPR ( 156, 158, 179) - RAIG ( 1, 2, 3, 4) - Taste receptors ( TAS1R ( 1, 2, 3) TAS2R ( 1, 3, 4, 5, 8, 9, 10, 12, 13, 14, 16, 38, 39, 40, 41, 43, 44, 45, 46, 47, 48, 49, 50))
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| Frizzled / Smoothened |
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