Lysyl hydroxylase
From Wikipedia, the free encyclopedia
|
procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1
|
|
| Identifiers | |
| Symbol | PLOD1 |
| Alt. Symbols | LLH, PLOD |
| Entrez | 5351 |
| HUGO | 9081 |
| OMIM | 153454 |
| RefSeq | NM_000302 |
| UniProt | Q02809 |
| Other data | |
| EC number | 1.14.11.4 |
| Locus | Chr. 1 p36.3-36.2 |
|
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
|
|
| Identifiers | |
| Symbol | PLOD2 |
| Entrez | 5352 |
| HUGO | 9082 |
| OMIM | 601865 |
| RefSeq | NM_000935 |
| UniProt | O00469 |
| Other data | |
| Locus | Chr. 3 q24 |
Lysyl hydroxylase (or procollagen-lysine 5-dioxygenase) is an oxygenase enzyme which catalyzes the hydroxylation of lysine to hydroxylysine. This reaction is involved in the formation and stabilization of collagen.
It requires vitamin C as a cofactor.
[edit] Pathology
A deficiency is associated with Ehlers-Danlos syndrome (type 6).
[edit] External links
 |
This oxidoreductase article is a stub. You can help Wikipedia by expanding it. |
|
||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
