D-cysteine desulfhydrase

From Wikipedia, the free encyclopedia

In enzymology, a D-cysteine desulfhydrase (EC 4.4.1.15) is an enzyme that catalyzes the chemical reaction

D-cysteine + H₂O sulfide + NH₃ + pyruvate

Thus, the two substrates of this enzyme are D-cysteine and H₂O, whereas its 3 products are sulfide, NH₃, and pyruvate.

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is D-cysteine sulfide-lyase (deaminating; pyruvate-forming). Other names in common use include D-cysteine lyase, and D-cysteine sulfide-lyase (deaminating). This enzyme participates in cysteine metabolism.

[edit] References

• IUBMB entry for 4.4.1.15
• BRENDA references for 4.4.1.15 (Recommended.)
• PubMed references for 4.4.1.15
• PubMed Central references for 4.4.1.15
• Google Scholar references for 4.4.1.15
• Nagasawa T, Ishii T, Kumagai H, Yamada H (1985). "D-Cysteine desulfhydrase of Escherichia coli. Purification and characterization". Eur. J. Biochem. 153: 541–51. doi:10.1111/j.1432-1033.1985.tb09335.x. PMID 3908101. 
• Schmidt A (1982). "A cysteine desulfhydrase from spinach leaves specific for D-cysteine". Z. Pflanzenphysiol. 107: 301–312. 
• Schmidt A and Erdle I (1983). "A cysteine desulfhydrase specific for D-cysteine from the green-alga Chlorella fusca". Z. Naturforsch. C: Biosci. 38: 428–435. 

[edit] External links

The CAS registry number for this enzyme class is 84012-74-8.

• IUBMB entry for 4.4.1.15

• KEGG entry for 4.4.1.15

• BRENDA entry for 4.4.1.15

• NiceZyme view of 4.4.1.15

• EC2PDB: PDB structures for 4.4.1.15

• PRIAM entry for 4.4.1.15

• PUMA2 entry for 4.4.1.15

• IntEnz: Integrated Enzyme entry for 4.4.1.15

• MetaCyc entry for 4.4.1.15

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0019148: D-cysteine desulfhydrase

• AMIGO entry for GO code 0019148: D-cysteine desulfhydrase