Stearoyl-CoA desaturase-1

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stearoyl-CoA desaturase (delta-9-desaturase)
Identifiers
Symbol	SCD
Entrez	6319
HUGO	10571
OMIM	604031
RefSeq	NM_005063
UniProt	O00767
Other data
EC number	1.14.19.1
Locus	Chr. 10 q23-q24

Stearoyl-CoA desaturase-1 is a key enzyme in fatty acid metabolism.

[edit] External links

• Rahman SM, Dobrzyn A, Dobrzyn P et al (2003). "Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle". Proc. Natl. Acad. Sci. U.S.A. 100 (19): 11110–5. doi:10.1073/pnas.1934571100. PMID 12960377. 
• MeSH Stearoyl-CoA+Desaturase

v • d • e Oxidoreductases: dioxygenases, including steroid hydroxylases (EC 1.14) 1.14.11 - 2-oxoglutarate Prolyl hydroxylase - Lysyl hydroxylase 1.14.13 - NADH or NADPH Flavin-containing monooxygenase - Nitric oxide synthase (NOS1, NOS2A, NOS3) - Cholesterol 7 alpha-hydroxylase - Methane monooxygenase - 3A4 -51A1 1.14.14 - reduced flavin or flavoprotein 19A1 - 2D6 - 2E1 1.14.15 - reduced iron-sulfur protein 11B1 - 11B2 - 11A1 1.14.16 - reduced pteridine Phenylalanine hydroxylase - Tyrosine hydroxylase - Tryptophan hydroxylase 1.14.17 - reduced ascorbate Dopamine beta hydroxylase 1.14.18-19 - other Tyrosinase - Stearoyl-CoA desaturase-1 1.14.99 - miscellaneous Cyclooxygenase - Heme oxygenase (HMOX1) - Squalene monooxygenase - 17A1 - 21A2