Isopentenyl-diphosphate delta isomerase

isopentenyl-diphosphate delta isomerase 1
Identifiers
Symbol	IDI1
Entrez	3422
HUGO	5387
OMIM	604055
RefSeq	NM_004508
UniProt	Q13907
Other data
EC number	5.3.3.2
Locus	Chr. 10 p15.3

Isopentenyl-diphosphate delta isomerase (or isopentenyl pyrophosphate isomerase) is an enzyme which catalyzes the conversion of 3-isopentenyl pyrophosphate to dimethylallyl pyrophosphate.

Conversion of 3-isopentenyl pyrophosphate to dimethylallyl pyrophosphate

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v • d • e Intramolecular oxidoreductases isomerases (EC 5.3)

5.3.1 - Aldoses/Ketoses	Triosephosphate isomerase - Phosphopentose isomerase - Mannose phosphate isomerase - Glucose isomerase

5.3.3 - C=C	Isopentenyl-diphosphate delta isomerase - Enoyl CoA isomerase

5.3.4 - S-S	Protein disulfide isomerase (PDIA3)

5.3.99 - other	Prostaglandin D2 synthase - Prostaglandin E synthase - Prostacyclin synthase - Thromboxane-A synthase

v • d • e Metabolism: lipid metabolism - ketones/mevalonate pathway/cholesterol synthesis enzymes

To HMG-CoA	Acetyl-Coenzyme A acetyltransferase - HMG-CoA synthase (regulated step)

Ketogenesis	HMG-CoA lyase - 3-hydroxybutyrate dehydrogenase - Thiophorase

To Mevalonic acid	HMG-CoA reductase

To DMAPP	Mevalonate kinase - Phosphomevalonate kinase - Pyrophosphomevalonate decarboxylase - Isopentenyl-diphosphate delta isomerase

To Cholesterols	Dimethylallyltranstransferase - Geranyl pyrophosphate - Farnesyl-diphosphate farnesyltransferase - Squalene monooxygenase - Lanosterol synthase - CYP51A1

To Bile acids	Cholesterol 7 alpha-hydroxylase

see also intermediates