Phosphopentose isomerase

From Wikipedia, the free encyclopedia

ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase)
Identifiers
Symbol	RPIA
Entrez	22934
HUGO	10297
OMIM	180430
RefSeq	NM_144563
UniProt	P49247
Other data
EC number	5.3.1.6
Locus	Chr. 2 p12-2p11

Phosphopentose isomerase is an enzyme which converts ribulose 5-phosphate (a ketose) to ribose 5-phosphate (an aldose).

In the pentose phosphate pathway, it converts the aldose to the ketose.

[edit] External links

• Diagram at stanford.edu
• Description and mechanism (click on link) at nih.gov
• EC 5.3.1.6
• MeSH ribosephosphate+isomerase

v • d • e Intramolecular oxidoreductases isomerases (EC 5.3) 5.3.1 - Aldoses/Ketoses Triosephosphate isomerase - Phosphopentose isomerase - Mannose phosphate isomerase - Glucose isomerase 5.3.3 - C=C Isopentenyl-diphosphate delta isomerase - Enoyl CoA isomerase 5.3.4 - S-S Protein disulfide isomerase (PDIA3) 5.3.99 - other Prostaglandin D2 synthase - Prostaglandin E synthase - Prostacyclin synthase - Thromboxane-A synthase

v • d • e Metabolism: carbohydrate metabolism - pentose phosphate pathway enzymes oxidative Glucose-6-phosphate dehydrogenase - 6-phosphogluconolactonase - Phosphogluconate dehydrogenase nonoxidative Phosphopentose isomerase - Phosphopentose epimerase - Transketolase - Transaldolase see also disorders