Enoyl CoA isomerase

dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)
Identifiers
Symbol	DCI
Entrez	1632
HUGO	2703
OMIM	600305
RefSeq	NM_001919
UniProt	P42126
Other data
EC number	5.3.3.8
Locus	Chr. 16 p13.3

Enoyl CoA isomerase (EC 5.3.3.8) is an enzyme that catalyzes conversion of cis-double bonds of fatty acids at position 3 to trans double bonds at position 2. It has a special importance in metabolism of unsaturated fatty acids.

[edit] See also

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v • d • e Intramolecular oxidoreductases isomerases (EC 5.3)

5.3.1 - Aldoses/Ketoses	Triosephosphate isomerase - Phosphopentose isomerase - Mannose phosphate isomerase - Glucose isomerase

5.3.3 - C=C	Isopentenyl-diphosphate delta isomerase - Enoyl CoA isomerase

5.3.4 - S-S	Protein disulfide isomerase (PDIA3)

5.3.99 - other	Prostaglandin D2 synthase - Prostaglandin E synthase - Prostacyclin synthase - Thromboxane-A synthase

v • d • e Metabolism: lipid metabolism - triglyceride and fatty acid enzymes

Lipid production	ATP citrate lyase - Acetyl-CoA carboxylase Fatty acid synthesis/Fatty acid synthase: Beta-ketoacyl-ACP synthase - Β-Ketoacyl ACP reductase - 3-Hydroxyacyl ACP dehydrase - Enoyl ACP reductase triacyl glycerol: Glycerol-3-phosphate dehydrogenase - Thiokinase

Lipid degradation	Acyl transport: Carnitine palmitoyltransferase I - Carnitine-acylcarnitine translocase - Carnitine palmitoyltransferase II Beta oxidation/Mitochondrial trifunctional protein: Acyl CoA dehydrogenase (ACADL, ACADM, ACADS, ACADVL) - Enoyl-CoA hydratase - 3-Hydroxyacyl CoA dehydrogenase - Acetyl-CoA C-acyltransferase to acetyl-CoA: Malonyl-CoA decarboxylase unsaturated (Enoyl CoA isomerase, 2,4 Dienoyl-CoA reductase) odd chain (Propionyl-CoA carboxylase) aldehydes (Long-chain-aldehyde dehydrogenase)

see also disorders