HDMP-28

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HDMP-28
Systematic (IUPAC) name
methyl (2R)-2-naphthalen-2-yl-2-[(2R)-piperidin-2-yl]acetate
Identifiers
CAS number  ?
ATC code  ?
PubChem 9817261
Chemical data
Formula C18H21NO2 
Mol. mass 283.365
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

HDMP-28 is a piperidine based stimulant drug. It is closely related to dexmethylphenidate, but with the phenyl ring replaced by naphthalene. It is a potent dopamine reuptake inhibitor, with several times the potency of methylphenidate and a short duration of action,[1] and is a structural isomer of another potent dopamine reuptake inhibitor, (-)-Methyl-1-methyl-4β-(2-naphthyl)piperidine-3β-carboxylate.



[edit] References

  1. ^ Lile JA, Wang Z, Woolverton WL, France JE, Gregg TC, Davies HM, Nader MA. The reinforcing efficacy of psychostimulants in rhesus monkeys: the role of pharmacokinetics and pharmacodynamics. Journal of Pharmacology and Experimental Therapeutics. 2003 Oct;307(1):356-66. PMID 12954808


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