Isometheptene

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Isometheptene
Systematic (IUPAC) name
N,6-dimethylhept-5-en-2-amine
Identifiers
CAS number	503-01-5
ATC code	A03AX10
PubChem	22297
Chemical data
Formula	C9H19N
Mol. mass	141.254 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Oral

Isometheptene (usually as isometheptene mucate) is a sympathomimetic amine sometimes used in the treatment of migraines and tension headaches due to its vasoconstricting properties, that is, it causes constriction (narrowing) of blood vessels (arteries and veins). Along with paracetamol and dichloralphenazone, it is one of the constituents of Amidrine.

[edit] Chemistry

Isometheptene is a monounsaturated aliphatic secondary amine.

v • d • e Drugs for functional gastrointestinal disorders (A03) Drugs for functional bowel disorders antimuscarinics: Mebeverine - Dicycloverine - Propantheline papaverine and derivatives: Papaverine - Drotaverine - Moxaverine acting on serotonin receptors: 5-HT3 antagonists (Alosetron, Cilansetron) - 5HT4 agonists (Mosapride, Tegaserod) other: Diisopromine - Isometheptene - Phloroglucinol - Proglumide - Tridihexethyl Belladonna and derivatives (antimuscarinics) Atropine - Hyoscyamine - Butylscopolamine - Methylscopolamine - Scopolamine - Tincture of Belladonna Propulsives primarily dopamine antagonists (Metoclopramide/Bromopride, Domperidone, Alizapride) - serotonin agonists (Cisapride) - Clebopride

v • d • e Sympathomimetic amines (R01, A08 and others) Alpha-pyrrolidinopropiophenone • Aminorex • d-Amphetamine & l,d-Amphetamine • d-Methamphetamine & l-Methamphetamine • Benzylpiperazine • Cathinone • CFT • Chlorphentermine • Clobenzorex • Cocaine • Cyclopentamine • Desoxypipradrol • Diethylpropion • Ephedrine • 4-FMP • 4-MTA • Fencamfamine • Fenfluramine • Fenproporex • Mazindol • MDPV • 4-Methyl-aminorex • Methylone • Methylphenidate • Naphazoline • Pemoline • Phendimetrazine • Phenmetrazine • Phentermine • Phenylephrine • Pipradrol • Pseudoephedrine • Pyrovalerone • Sibutramine • Synephrine See also amphetamines