Delorazepam

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Delorazepam
Systematic (IUPAC) name
(7-Chloro-5-(o-chlorophenyl) -1,3-dihydro-2H-1,4-benzodiazepin-2-one)
Identifiers
CAS number	?
ATC code	?
PubChem	17925
DrugBank	?
Chemical data
Formula	C15H10Cl2N2O
Mol. mass	304.02
Pharmacokinetic data
Bioavailability	87%
Metabolism	Hepatic
Half life	[60-140]
Excretion	Renal
Therapeutic considerations
Pregnancy cat.	?
Legal status	?
Routes	Oral

Delorazepam also known as chlordesmethyldiazepam is a drug which is a benzodiazepine derivative. It's mainly used in Italy, where is available under trade name "En".

The potency of delorazepam is very high, and probably 1 mg delorazepam equals 10 mg diazepam.

In adult half life is 99.7 (±22.3) hours for cpr and 96.9 (±19.7) hours for drops afetr a single dose of 1 mg. In children half life is about 40 hours for children of 7 months, 27 hours for children between 2 and 3 years, 34 hours for more than 3 years.

Total clearance afrt single administration of 2 mg is 0.11 ml/min/kg.

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