Fletazepam

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Fletazepam
Systematic (IUPAC) name
7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1,4-benzodiazepine
Identifiers
CAS number	34482-99-0
ATC code	?
PubChem	36834
Chemical data
Formula	C17H13ClF4N2
Mol. mass	356.745
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Fletazepam is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is mainly notable for its strong muscle relaxant properties.^[1]

Fletazepam is most closely related to other N-trifluoroethyl substituted benzodiazepines such as halazepam and quazepam.^[2]

[edit] References

1. ^ Barnett A, Goldstein J, Fiedler EP, Taber RI. The pharmacology of fletazepam, a centrally-acting muscle relaxant. Archives Internationales de Pharmacodynamie et de Therapie. 1974 Nov;212(1):164-74.
2. ^ Orio LC, Barnett A, Billard W. Selective affinity of 1-N-trifluoroethyl benzodiazepines for cerebellar type 1 receptor sites. Life Sciences, 1984. (35):105-113.

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