Triflubazam

From Wikipedia, the free encyclopedia

Triflubazam
Systematic (IUPAC) name
5-methyl-1-phenyl-8-(trifluoromethyl)-1,5-benzodiazepine-2,4-dione
Identifiers
CAS number	22365-40-8
ATC code	?
PubChem	31157
Chemical data
Formula	C17H13F3N2O2
Mol. mass	334.29
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Triflubazam is a drug which is a 1,5-benzodiazepine derivative, related to clobazam. It has sedative and anxiolytic effects, with a long half-life and duration of action.^[1][2][3]

[edit] References

1. ^ Itil TM, Akpinar S, Fink M: Controlled clinical and quantitative EEG studies of triflubazam (ORF 8063) in patients with anxiety syndrome. Current Therapeutic Research 1976; 19: 307-315
2. ^ Csanalosi I, Pereira-Oran J, Case G, et al: Triflubazam (ORF 8063), a new benzodiazepine in anxiety neurosis. Current Therapeutic Research 1977; 22: 166-171
3. ^ Nicholson AN, Stone BM, Clarke CH. Effect of the 1,5-benzodiazepines, clobazam and triflubazam, on sleep in man. British Journal of Clinical Pharmacology. 1977 Oct;4(5):567-72.

[1]

v • d • e Benzodiazepines (N05BA, N05CD) 1,4-Benzodiazepines Bromazepam • Camazepam • Chlordiazepoxide • Cinolazepam • Clonazepam • Clorazepate • Cyprazepam • Delorazepam • Diazepam • Doxefazepam • Elfazepam • Ethyl loflazepate • Fletazepam • Fludiazepam • Fosazepam • Flunitrazepam • Flurazepam • Flutoprazepam • Gidazepam • Halazepam • Iclazepam • Lorazepam • Lormetazepam • Meclonazepam • Medazepam • Menitrazepam • Metaclazepam • Nimetazepam • Nitrazepam • Nordazepam • Oxazepam • Phenazepam • Pinazepam • Pivoxazepam • Prazepam • Premazepam • Quazepam • QH-II-66 • Reclazepam • Sulazepam • Temazepam • Tetrazepam • Uldazepam Triazolobenzodiazepines Adinazolam • Alprazolam • Estazolam • Triazolam • Zapizolam Imidazobenzodiazepines Bretazenil • Flumazenil • Imidazenil • Loprazolam • Midazolam • Ro15-4513 • Ro48-6791 Oxazolobenzodiazepines Cloxazolam • Flutazolam • Haloxazolam • Mexazolam • Oxazolam Thienobenzodiazepines Brotizolam • Clotiazepam • Etizolam 1,5-Benzodiazepines Arfendazam • Clobazam • Lofendazam • Razobazam • Triflubazam 2,3-Benzodiazepines Girisopam • GYKI-52895 • Nerisopam • Tofisopam Benzodiazepine Prodrugs Avizafone • Rilmazafone Others Bentazepam • Ketazolam • Olanzepine • Tifluadom • Zolazepam