D-lactate dehydrogenase (cytochrome c-553)

From Wikipedia, the free encyclopedia

In enzymology, a D-lactate dehydrogenase (cytochrome c-553) (EC 1.1.2.5) is an enzyme that catalyzes the chemical reaction

(R)-lactate + 2 ferricytochrome c-553 pyruvate + 2 ferrocytochrome c-553

Thus, the two substrates of this enzyme are (R)-lactate and ferricytochrome c-553, whereas its two products are pyruvate and ferrocytochrome c-553.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is (R)-lactate:ferricytochrome-c-553 2-oxidoreductase. This enzyme participates in pyruvate metabolism.

[edit] References

• IUBMB entry for 1.1.2.5
• BRENDA references for 1.1.2.5 (Recommended.)
• PubMed references for 1.1.2.5
• PubMed Central references for 1.1.2.5
• Google Scholar references for 1.1.2.5
• Ogata M, Arihara K and Yagi T (Tokyo). "D-Lactate dehydrogenase of Desulfovibrio vulgaris". J. Biochem.: 1423–1431. 

[edit] External links

The CAS registry number for this enzyme class is 37250-79-6.

• IUBMB entry for 1.1.2.5

• KEGG entry for 1.1.2.5

• BRENDA entry for 1.1.2.5

• NiceZyme view of 1.1.2.5

• EC2PDB: PDB structures for 1.1.2.5

• PRIAM entry for 1.1.2.5

• PUMA2 entry for 1.1.2.5

• IntEnz: Integrated Enzyme entry for 1.1.2.5

• MetaCyc entry for 1.1.2.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047051: D-lactate dehydrogenase (cytochrome c-553)

• AMIGO entry for GO code 0047051: D-lactate dehydrogenase (cytochrome c-553)

v • d • e Oxidoreductases: alcohol oxidoreductases (EC 1.1) 1.1.1 NAD/NADP acceptor Carbohydrate dehydrogenases - Alcohol dehydrogenase - Glycerol-3-phosphate dehydrogenase - L-xylulose reductase - Aldose reductase - Lactate dehydrogenase - 3-Hydroxyacyl CoA dehydrogenase - Malate dehydrogenase - Isocitrate dehydrogenase - Phosphogluconate dehydrogenase - Glucose-6-phosphate dehydrogenase - HMG-CoA reductase - Β-Ketoacyl ACP reductase - Hydroxysteroid dehydrogenase: 11 Beta (HSD11B1, HSD11B2) - 3 Beta (3-beta-HSD) - 17 Beta - Carnitine dehydrogenase - Beta-hydroxybutyryl-CoA dehydrogenase - IMP dehydrogenase - DXP reductoisomerase - L-threonine dehydrogenase 1.1.2 cytochrome acceptor Mannitol dehydrogenase (cytochrome) - D-lactate dehydrogenase (cytochrome) - D-lactate dehydrogenase (cytochrome c-553) 1.1.3 oxygen acceptor Glucose oxidase - L-gulonolactone oxidase - Xanthine oxidase 1.1.4 disulfide as acceptor Vitamin K epoxide reductase - Vitamin-K-epoxide reductase (warfarin-insensitive) 1.1.5 quinone/similar acceptor Quinoprotein glucose dehydrogenase 1.1.99 other acceptors Choline dehydrogenase