Thiofentanyl

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Thiofentanyl
Systematic (IUPAC) name
N-phenyl-N-[1-(2-thiophen-2-ylethyl)-4-piperidyl]propanamide
Identifiers
CAS number	60771-38-2
ATC code	?
PubChem	62380
Chemical data
Formula	C20H26N2OS
Mol. mass	342.499 g/mol
Synonyms	Thiofentanyl
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	Schedule I(CA) Class A(UK) Schedule I(US)
Routes	?

Thiofentanyl is an opioid analgesic that is an analogue of fentanyl.

Thiofentanyl was sold briefly on the black market in the early 1980s, before the introduction of the Federal Analog Act which for the first time attempted to control entire families of drugs based on their structural similarity rather than scheduling each drug individually as they appeared. ^[1] Thiofentanyl is made with the same synthetic route as fentanyl, but by substituting 2-(2-bromoethyl)thiophene for phenethyl bromide in the synthesis.

Thiofentanyl has similar effects to fentanyl. Side effects of fentanyl analogues are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression which can be life-threatening.

[edit] References

1. ^ Henderson GL. Designer Drugs: Past History and Future Prospects. Journal of Forensic Sciences 1988; 33(2):569-575

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