Sitafloxacin

Sitafloxacin

IUPAC name	7-[(4S)-4-amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid
Other names	DU-6859a
Identifiers
CAS number	[127254-12-0]
PubChem	73011
SMILES	C1CC12CN(CC2N)C3=C(C=C4C(=C3Cl) N(C=C(C4=O)C(=O)O)C5CC5F)F
Properties
Molecular formula	C₁₉H₁₈ClF₂N₃O₃
Molar mass	409.814326
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Sitafloxacin (also called DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. The molecule was identified by Daiichi Pharmaceutical Co. Ltd, who have also brought ofloxacin and levofloxacin to the market. Sitafloxacin is currently under development in Japan.

v • d • e Antibacterials for systemic use: quinolones (J01M)

Fluoroquinolones	Alatrofloxacin^‡ • Ciprofloxacin • Danofloxacin^§ • Difloxacin^§ • Enoxacin • Enrofloxacin^§ • Fleroxacin^‡ • Garenoxacin • Gatifloxacin • Gemifloxacin • Grepafloxacin^‡ • Ibafloxacin^§ • Levofloxacin • Lomefloxacin • Marbofloxacin^§ • Moxifloxacin • Norfloxacin • Ofloxacin • Orbifloxacin^§ • Pazufloxacin • Pefloxacin • Pradofloxacin^§ • Prulifloxacin • Rufloxacin • Sarafloxacin^§ • Sitafloxacin^† • Sparfloxacin • Temafloxacin^‡ • Tosufloxacin • Trovafloxacin^‡

Other quinolones	Cinoxacin • Flumequine^§ • Nalidixic acid • Oxolinic acid • Pipemidic acid • Piromidic acid • Rosoxacin

^†Undergoing clinical trials. ^‡ Withdrawn from market. ^§ Veterinary use medications.

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