Garenoxacin

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Garenoxacin
Systematic (IUPAC) name
1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxoquinoline-3-carboxylic acid
Identifiers
CAS number 91421-42-0
ATC code J01MA19
PubChem 124093
Chemical data
Formula C23H20F2N2O4 
Mol. mass 426.412 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes Oral

Garenoxacin (INN) is a quinolone antibiotic for the treatment of gram-positive and gram-negative bacterial infections.

It was discovered by Toyama Chemical Co., Ltd. of Tokyo, Japan, and is currently being marketed in Japan under the tradename Geninax. Schering-Plough holds worldwide rights for garenoxacin, excepf for Japan, South Korea, and China.

On February 13, 2006, Schering-Plough announced that the United States Food and Drug Administration has accepted the New Drug Application (NDA) for garenoxacin, and has been granted a 10-month review.[1]

[edit] References

  1. ^ Drugs.com, Schering-Plough Reports Garenoxacin NDA Accepted for FDA Review. Retrieved on 2008-03-25.
v • d • e
Antibacterials for systemic use: quinolones (J01M)
Fluoroquinolones
Alatrofloxacin‡ • Ciprofloxacin • Danofloxacin§ • Difloxacin§ • Enoxacin • Enrofloxacin§ • Fleroxacin‡ • Garenoxacin • Gatifloxacin • Gemifloxacin • Grepafloxacin‡ • Ibafloxacin§ • Levofloxacin • Lomefloxacin • Marbofloxacin§ • Moxifloxacin • Norfloxacin • Ofloxacin • Orbifloxacin§ • Pazufloxacin • Pefloxacin • Pradofloxacin§ • Prulifloxacin • Rufloxacin • Sarafloxacin§ • Sitafloxacin† • Sparfloxacin • Temafloxacin‡ • Tosufloxacin • Trovafloxacin‡
Other quinolones
†Undergoing clinical trials. ‡ Withdrawn from market. § Veterinary use medications.
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