Lomefloxacin

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Lomefloxacin
Systematic (IUPAC) name
1-ethyl-6,8-difluoro- 7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3- carboxylic acid
Identifiers
CAS number 98079-51-7
ATC code J01MA07 S01AX17
PubChem 3948
DrugBank APRD01076
Chemical data
Formula C17H19F2N3O3 
Mol. mass 351.348 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 10%
Metabolism  ?
Half life 8 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Lomefloxacin hydrochloride (Maxaquin) is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery. It is taken orally, usually daily for 10-14 days.

Lomefloxacin is unique in that it forms a magnesium chelate with itself. The chelate is formed between the 2-carbonyl group of two separate lomefloxacin molecules.

v • d • e
Antibacterials for systemic use: quinolones (J01M)
Fluoroquinolones
Alatrofloxacin‡ • Ciprofloxacin • Danofloxacin§ • Difloxacin§ • Enoxacin • Enrofloxacin§ • Fleroxacin‡ • Garenoxacin • Gatifloxacin • Gemifloxacin • Grepafloxacin‡ • Ibafloxacin§ • Levofloxacin • Lomefloxacin • Marbofloxacin§ • Moxifloxacin • Norfloxacin • Ofloxacin • Orbifloxacin§ • Pazufloxacin • Pefloxacin • Pradofloxacin§ • Prulifloxacin • Rufloxacin • Sarafloxacin§ • Sitafloxacin† • Sparfloxacin • Temafloxacin‡ • Tosufloxacin • Trovafloxacin‡
Other quinolones
†Undergoing clinical trials. ‡ Withdrawn from market. § Veterinary use medications.
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