Phosphoglycerate kinase

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phosphoglycerate kinase 1

Enzyme Phosphoglycerate kinase
PDB Code PDB 3PGK
Organism Yeast
Symbol(s): PGK1
Genetic data
Locus: Chr. X q13.3
Database Links
EC number: 2.7.2.3
Entrez: 5230
OMIM: 311800
RefSeq: NM_000291
UniProt: P00558
phosphoglycerate kinase 2
Symbol(s): PGK2
Genetic data
Locus: Chr. 6 p21-q12
Database Links
Entrez: 5232
OMIM: 172270
RefSeq: NM_138733
UniProt: P07205

Phosphoglycerate kinase is a transferase enzyme used in the seventh step of glycolysis.

It transfers a phosphate group from 1,3-biphosphoglycerate to ADP, forming ATP and 3-Phosphoglycerate.

1,3-Bisphosphoglycerate

Glycerate 3-phosphate

[edit] External links

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Glycolysis Metabolic Pathway
Glucose Hexokinase Glucose-6-phosphate Glucose-6-phosphate isomerase Fructose 6-phosphate 6-phosphofructokinase Fructose 1,6-bisphosphate Fructose bisphosphate aldolase Dihydroxyacetone phosphate Glyceraldehyde 3-phosphate Triosephosphate isomerase Glyceraldehyde 3-phosphate Glyceraldehyde-3-phosphate dehydrogenase
ATP ADP ATP ADP NAD+ + Pi NADH + H+
+ 2
NAD+ + Pi NADH + H+
1,3-Bisphosphoglycerate Phosphoglycerate kinase 3-Phosphoglycerate Phosphoglycerate mutase 2-Phosphoglycerate Phosphopyruvate hydratase(Enolase) Phosphoenolpyruvate Pyruvate kinase Pyruvate Pyruvate dehydrogenase Acetyl-CoA
ADP ATP H2O ADP ATP CoA + NAD+ NADH + H+ + CO2
2 2 2 2 2 2
ADP ATP H2O
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Metabolism: carbohydrate metabolism: glycolysis/gluconeogenesis enzymes
Glycolysis
Gluconeogenesis only
Regulatory
see also disorders
v • d • e
Transferases: Phosphotransferases/kinases (EC 2.7)
2.7.1 - OH acceptor
2.7.2 - COOH acceptor
Phosphoglycerate - Aspartate
2.7.3 - N acceptor
2.7.4 - PO4 acceptor
2.7.6 - P2O7
2.7.7 - nucleotidyl-
2.7.8 - other phos.
2.7.10-11 - protein
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