Ribose-phosphate diphosphokinase

phosphoribosyl pyrophosphate synthetase 1
Identifiers
Symbol	PRPS1
Entrez	5631
HUGO	9462
OMIM	311850
RefSeq	NM_002764
UniProt	P60891
Other data
EC number	2.4.2.17
Locus	Chr. X q21-q27

phosphoribosyl pyrophosphate synthetase 2
Identifiers
Symbol	PRPS2
Entrez	5634
HUGO	9465
OMIM	311860
RefSeq	NM_002765
UniProt	P11908
Other data
EC number	2.4.2.17
Locus	Chr. X pter-q21

Ribose-phosphate diphosphokinase (or phosphoribosyl pyrophosphate synthetase) is an enzyme which converts ribose 5-phosphate into phosphoribosyl pyrophosphate.

It is classified under EC 2.7.6.1.

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v • d • e Transferases: Phosphotransferases/kinases (EC 2.7)

2.7.1 - OH acceptor	Hexo- - Gluco- - Fructo- (Hepatic fructo-) - Galacto- - Phosphofructo- (1, 2) - Riboflavin - Shikimate - Thymidine - NAD⁺ - Glycerol - Pantothenate - Mevalonate - Pyruvate - Deoxycytidine - PFP - Diacylglycerol - Bruton's tyrosine - Phosphoinositide 3 (Class I PI 3, Class II PI 3) - Sphingosine

2.7.2 - COOH acceptor	Phosphoglycerate - Aspartate

2.7.3 - N acceptor	Creatine

2.7.4 - PO₄ acceptor	Phosphomevalonate - Adenylate - Nucleoside-diphosphate

2.7.6 - P₂O₇	Ribose-phosphate diphosphokinase - Thiamine pyrophosphokinase

2.7.7 - nucleotidyl-	Integrase - PNPase - Polymerase - RNase PH - UDP-glucose pyrophosphorylase - Galactose-1-phosphate uridylyltransferase -Terminal deoxynucleotidyl transferase - RNA replicase - Reverse transcriptase (Telomerase) - Transposase

2.7.8 - other phos.	N-acetylglucosamine-1-phosphate transferase

2.7.10-11 - protein	Tyrosine - Serine/threonine-specific