Hot 100 number-one hits of 1961 (United States)
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These are the Billboard magazine Hot 100 number one hits of 1961.
| Issue Date | Song | Artist |
| January 2 | "Are You Lonesome Tonight?" | Elvis Presley |
| January 9 | "Wonderland by Night" | Bert Kaempfert |
| January 16 | "Wonderland by Night" | Bert Kaempfert |
| January 23 | "Wonderland by Night" | Bert Kaempfert |
| January 30 | "Will You Love Me Tomorrow" | The Shirelles |
| February 6 | "Will You Love Me Tomorrow" | The Shirelles |
| February 13 | "Calcutta" | Lawrence Welk |
| February 20 | "Calcutta" | Lawrence Welk |
| February 27 | "Pony Time" | Chubby Checker |
| March 6 | "Pony Time" | Chubby Checker |
| March 13 | "Pony Time" | Chubby Checker |
| March 20 | "Surrender" | Elvis Presley |
| March 27 | "Surrender" | Elvis Presley |
| April 3 | "Blue Moon" | The Marcels |
| April 10 | "Blue Moon" | The Marcels |
| April 17 | "Blue Moon" | The Marcels |
| April 24 | "Runaway" | Del Shannon |
| May 1 | "Runaway" | Del Shannon |
| May 8 | "Runaway" | Del Shannon |
| May 15 | "Runaway" | Del Shannon |
| May 22 | "Mother-in-Law" | Ernie K-Doe |
| May 29 | "Travelin' Man" | Ricky Nelson |
| June 5 | "Running Scared" | Roy Orbison |
| June 12 | "Travelin' Man" | Ricky Nelson |
| June 19 | "Moody River" | Pat Boone |
| June 26 | "Quarter to Three" | Gary U.S. Bonds |
| July 3 | "Quarter to Three" | Gary U.S. Bonds |
| July 10 | "Tossin' and Turnin'" | Bobby Lewis |
| July 17 | "Tossin' and Turnin'" | Bobby Lewis |
| July 24 | "Tossin' and Turnin'" | Bobby Lewis |
| July 31 | "Tossin' and Turnin'" | Bobby Lewis |
| August 7 | "Tossin' and Turnin'" | Bobby Lewis |
| August 14 | "Tossin' and Turnin'" | Bobby Lewis |
| August 21 | "Tossin' and Turnin'" | Bobby Lewis |
| August 28 | "Wooden Heart (Muss I Denn)" | Joe Dowell |
| September 4 | "Michael" | The Highwaymen |
| September 11 | "Michael" | The Highwaymen |
| September 18 | "Take Good Care of My Baby" | Bobby Vee |
| September 25 | "Take Good Care of My Baby" | Bobby Vee |
| October 2 | "Take Good Care of My Baby" | Bobby Vee |
| October 9 | "Hit the Road Jack" | Ray Charles |
| October 16 | "Hit the Road Jack" | Ray Charles |
| October 23 | "Runaround Sue" | Dion |
| October 30 | "Runaround Sue" | Dion |
| November 6 | "Big Bad John" | Jimmy Dean |
| November 13 | "Big Bad John" | Jimmy Dean |
| November 20 | "Big Bad John" | Jimmy Dean |
| November 27 | "Big Bad John" | Jimmy Dean |
| December 4 | "Big Bad John" | Jimmy Dean |
| December 11 | "Please Mr. Postman" | The Marvelettes |
| December 18 | "The Lion Sleeps Tonight" | The Tokens |
| December 25 | "The Lion Sleeps Tonight" | The Tokens |
