Cyanocobalamin

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Cyanocobalamin
Identifiers
CAS number [68-19-9]
PubChem 16212801
EINECS number 200-680-0
Properties
Molecular formula C63H88CoN14O14P
Molar mass 1355.38 g/mol
Appearance Dark red solid
Melting point

> 300 ° C

Boiling point

> 300 ° C

Solubility in water Soluble
Hazards
MSDS External MSDS from Fisher Scientific
EU classification Not available
NFPA 704
1
1
 
 
S-phrases S24/25
Flash point N/A
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Cyanocobalamin is an especially common "vitamer" (that is, member of a family of vitamins, all of which have some particular nutritional activity in preventing some vitamin deficiency disease) of the B-12 vitamin family. It is the most famous vitamer of the family, because it is chemically the most air-stable, and it is the easiest to crystallize and therefore easiest to purify after it is produced by bacterial fermentation. The cyanide is added to the molecule by activated charcoal columns in purification. Thus, the use of this form of B-12 is the most wide-spread.[1]

This fact has caused some people (usually from reading labels on packages and vitamin supplements, in which vitamin B-12 is almost always listed last, since ingredients by law are listed in order of weight %), to infer that the "correct" chemical name of vitamin B-12 actually is cyanocobalamin. In fact, "vitamin B-12" is the name for a whole class of chemicals with B-12 activity, and "cyanocobalamin" is only one of these. Cyanocobalamin usually does not even occur in nature, and cyanocobalamin is not one of the forms of this vitamin which is directly used in the human body (or that of any other animal). However, animals and humans can convert it to active (cofactor) forms of the vitamin, such as methylcobalamin.[1]

[edit] References

  1. ^ a b Victor Herbert (1988). "Vitamin B-12: plant sources, requirements, and assay". American Journal of Clinical Nutrition 48: 852–8.