Tacalcitol

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Tacalcitol
Systematic (IUPAC) name
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5R)-5-hydroxy-6-methylheptan-2-yl ]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methyli denecyclohexane-1,3-diol
Identifiers
CAS number	57333-96-7
ATC code	D05AX04
PubChem	5283734
Chemical data
Formula	C27H44O3
Mol. mass	416.64
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Topical

Tacalcitol is a synthetic vitamin D₃ analogue that is used to treat psoriasis. Tacalcitol exerts its biological activity by preventing the proliferation of keratinocytes. Tacalcitol is marketed under several names, including Curatoderm and Bonalfa.

[edit] References

v • d • e Antipsoriatics (D05) Topical: tars Tar Topical: antracens Dithranol Topical: psoralens Trioxysalen - Methoxsalen Topical: other Fumaric acid - vitamin D (Calcipotriol, Calcitriol, Tacalcitol) - Tazarotene Systemic: psoralens Trioxysalen - Methoxsalen - Bergapten Systemic: retinoids Etretinate - Acitretin