Monobactams

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Aztreonam. (The square is the beta-lactam. There is a second thiazole ring, but it is not fused to the beta-lactam ring)

Monobactams are beta-lactam antibiotics wherein the beta-lactam ring is alone, and not fused to another ring (in contrast to most other beta-lactams, which have at least two rings). The only commercially available monobactam is aztreonam.

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MeSH Monobactams

v • d • e Antibacterials for systemic use: beta-lactam antibiotics - cephalosporins and related (J01D)

First generation	Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole

Second generation	Cefaclor, Cefamandole, Cefmetazole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime

Third generation	Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Ceftibuten, Ceftizoxime, Ceftriaxone, Latamoxef

Fourth generation	Cefepime, Cefozopran, Cefpirome, Cefquinome

Fifth generation	Ceftobiprole

Other beta-lactam antibacterials	Monobactams (Aztreonam), Carbapenems (Parenteral - Doripenem, Ertapenem, Imipenem, Meropenem, Panipenem, Oral - Faropenem)