Ceforanide


Ceforanide
Systematic (IUPAC) name
(6R,7R)-7-{[2-[2-(aminomethyl)phenyl]acetyl]amino}-3- {[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl}-8-oxo- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Identifiers
CAS number	60925-61-3
ATC code	J01DC11
PubChem	43507
DrugBank	APRD00853
Chemical data
Formula	C₂₀H₂₁N₇O₆S₂
Mol. mass	519.556 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	80.6%
Metabolism	Nil
Half life	2.6 to 2.98 hours
Excretion	Renal
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Intramuscular

Ceforanide is a second-generation cephalosporin antibiotic.

[edit] External links

Crowle A, Sbarbaro J, May M (1988). "Effects of isoniazid and of ceforanide against virulent tubercle bacilli in cultured human macrophages.". Tubercle 69 (1): 15–25. doi:10.1016/0041-3879(88)90036-0. PMID 3140456.
Campoli-Richards D, Lackner T, Monk J (1987). "Ceforanide. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy.". Drugs 34 (4): 411–37. PMID 3315624.
Cone L, Barton S, Woodard D (1987). "Treatment of scleroma with ceforanide.". Arch Otolaryngol Head Neck Surg 113 (4): 374–6. PMID 3814386.

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v • d • e Antibacterials for systemic use: beta-lactam antibiotics - cephalosporins and related (J01D)

First generation	Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole

Second generation	Cefaclor, Cefamandole, Cefmetazole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime

Third generation	Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Ceftibuten, Ceftizoxime, Ceftriaxone, Latamoxef

Fourth generation	Cefepime, Cefozopran, Cefpirome, Cefquinome

Fifth generation	Ceftobiprole

Other beta-lactam antibacterials	Monobactams (Aztreonam), Carbapenems (Parenteral - Doripenem, Ertapenem, Imipenem, Meropenem, Panipenem, Oral - Faropenem)