Cefprozil

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Cefprozil
Systematic (IUPAC) name
8-[2-amino-2-(4-hydroxyphenyl)-acetyl] amino-7-oxo-4-prop-1-enyl-2-thia-6- azabicyclo [ 4.2.0]oct-4-ene-5-carboxylic acid
Identifiers
CAS number	92665-29-7
ATC code	J01DC10
PubChem	5281006
DrugBank	APRD00461
Chemical data
Formula	C18H19N3O5S
Mol. mass	389.427 g/mol
Pharmacokinetic data
Bioavailability	95%
Protein binding	36%
Metabolism	?
Half life	1.3 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	Category-B
Legal status
Routes	ORAL

Cefprozil, sometimes spelled cefproxil and sold under the brand name Cefzil, is a cephalosporin type antibiotic. In Europe, it is sold by the name Procef. It can be used to treat bronchitis, ear infections, skin infections, and other bacterial infections. It comes as a tablet and as a liquid suspension.

Although there is a widely quoted cross-allergy risk of 10% between cephalosporins and penicillin, an article in the Journal of Family Practice (February 2006)^[1] has shown no increased risk for cross-allergy for cefprozil and several other 2nd generation or later cephalosporins.

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• Information about Cefprozil

v • d • e Antibacterials for systemic use: beta-lactam antibiotics - cephalosporins and related (J01D) First generation Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole Second generation Cefaclor, Cefamandole, Cefmetazole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime Third generation Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Ceftibuten, Ceftizoxime, Ceftriaxone, Flomoxef, Latamoxef Fourth generation Cefepime, Cefozopran, Cefpirome, Cefquinome Fifth generation Ceftobiprole Other beta-lactam antibacterials Monobactams (Aztreonam), Carbapenems (Parenteral - Doripenem, Ertapenem, Imipenem, Meropenem, Panipenem, Oral - Faropenem)