Gliquidone

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Gliquidone
Systematic (IUPAC) name
3-cyclohexyl-1-[4-[2-(7-methoxy-4,4-dimethyl-1,3- dioxo-isoquinolin-2-yl)ethyl]phenyl]sulfonyl-urea
Identifiers
CAS number	33342-05-1
ATC code	A10BB08
PubChem	91610
Chemical data
Formula	C27H33N3O6S
Mol. mass	527.634 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	95% Biliary, 5% Renal
Therapeutic considerations
Pregnancy cat.	?
Legal status	POM(UK)
Routes	Oral

Gliquidone (INN, sold under the trade name Glurenorm) is an anti-diabetic drug in the sulfonylurea class. It is used in the treatment of diabetes mellitus type 2.

v • d • e Oral antidiabetic drugs and Insulin analogs (A10) Biguanides Metformin Sulfonylureas Carbutamide, Chlorpropamide, Glibenclamide (Glyburide), Gliclazide, Glimepiride, Glipizide, Gliquidone, Tolazamide, Tolbutamide Alpha-glucosidase inhibitors Acarbose, Miglitol, Voglibose Thiazolidinediones (TZD) Pioglitazone, Rivoglitazone†, Rosiglitazone, Troglitazone‡ Meglitinides Nateglinide, Repaglinide, Mitiglinide Dipeptidyl peptidase-4 (DPP-4) inhibitors Alogliptin†, Saxagliptin†, Sitagliptin, Vildagliptin Glucagon-like peptide-1 analog Exenatide, Liraglutide†, Albiglutide† Amylin analog Pramlintide Insulin analogs fast acting (Insulin lispro, Insulin aspart, Insulin glulisine), long acting (Insulin glargine, Insulin detemir), Inhalable insulin (Exubera) Dual PPAR agonists Aleglitazar†, Muraglitazar§, Tesaglitazar§ SGLT2 inhibitor Dapagliflozin†, Remogliflozin†, Sergliflozin† †Undergoing clinical trials. ‡ Withdrawn from market. §Development halted.