CRTC2
From Wikipedia, the free encyclopedia
|
CREB regulated transcription coactivator 2
|
|||||
| Identifiers | |||||
| Symbol(s) | CRTC2; RP11-422P24.6; TORC2 | ||||
| External IDs | OMIM: 608972 MGI: 1921593 HomoloGene: 18765 | ||||
|
|||||
| Orthologs | |||||
| Human | Mouse | ||||
| Entrez | 200186 | 74343 | |||
| Ensembl | ENSG00000160741 | ENSMUSG00000027936 | |||
| Refseq | NM_181715 (mRNA) NP_859066 (protein) |
NM_028881 (mRNA) NP_083157 (protein) |
|||
| Location | Chr 1: 152.19 - 152.2 Mb | Chr 3: 90.34 - 90.35 Mb | |||
| Pubmed search | [1] | [2] | |||
CREB regulated transcription coactivator 2, also known as CRTC2, is a human gene.[1]
[edit] References
[edit] Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:. PMID 12477932.
- Iourgenko V, Zhang W, Mickanin C, et al. (2003). "Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.". Proc. Natl. Acad. Sci. U.S.A. 100 (21): 12147-52. doi:. PMID 14506290.
- Conkright MD, Canettieri G, Screaton R, et al. (2003). "TORCs: transducers of regulated CREB activity.". Mol. Cell 12 (2): 413-23. PMID 14536081.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:. PMID 14702039.
- Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.". Curr. Biol. 14 (16): 1436-50. doi:. PMID 15324660.
- Screaton RA, Conkright MD, Katoh Y, et al. (2004). "The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.". Cell 119 (1): 61-74. doi:. PMID 15454081.
- Al-Hakim AK, Göransson O, Deak M, et al. (2006). "14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.". J. Cell. Sci. 118 (Pt 23): 5661-73. doi:. PMID 16306228.
- Siu YT, Chin KT, Siu KL, et al. (2006). "TORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeats.". J. Virol. 80 (14): 7052-9. doi:. PMID 16809310.
- Wu Z, Huang X, Feng Y, et al. (2006). "Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells.". Proc. Natl. Acad. Sci. U.S.A. 103 (39): 14379-84. doi:. PMID 16980408.
- Yang Q, Inoki K, Ikenoue T, Guan KL (2006). "Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity.". Genes Dev. 20 (20): 2820-32. doi:. PMID 17043309.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:. PMID 17353931.
- Ravnskjaer K, Kester H, Liu Y, et al. (2007). "Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression.". EMBO J. 26 (12): 2880-9. doi:. PMID 17476304.
- Kuraishy AI, French SW, Sherman M, et al. (2007). "TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation.". Proc. Natl. Acad. Sci. U.S.A. 104 (24): 10175-80. doi:. PMID 17548807.
[edit] External links
|
|||||||||||

