Chemotherapy regimens

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Chemotherapy regimens are often identified with acronyms, identifying the agents used in combination. Unfortunately, the letters used are not consistent across regimens, and in some cases (for example, "BEACOPP") the same letter is used to represent two different treatments. Because of this, there is not a naming standard for chemotherapy regimens, and this page merely represents commonly used conventions.

The term "Induction regimens" refers to a chemotherapy regimen which is used for the initial treatment of a disease.

Name	Components	Example of uses, and other notes
ABVD	Adriamycin (doxorubicin), bleomycin, vinblastine, dacarbazine	Hodgkin's lymphoma
AC	Adriamycin (doxorubicin), cyclophosphamide	Breast cancer
BEACOPP	Bleomycin, etoposide, Adriamycin (doxorubicin), cyclophosphamide, Oncovin (vincristine), procarbazine, prednisone	Hodgkin's lymphoma
BEP	Bleomycin, etoposide, platinum agent (cisplatin)	Testicular cancer, germ cell tumors
CAF	Cyclophosphamide, Adriamycin (doxorubicin), fluorouracil (5-FU)	Breast cancer
CAV	Cyclophosphamide, Adriamycin (doxorubicin), vincristine	Lung cancer
CBV	Cyclophosphamide, BCNU (carmustine), VP-16 (etoposide)	Lymphoma
ChlVPP/EVA	Chlorambucil, vincristine (Oncovin), procarbazine, prednisone, etoposide, vinblastine, Adriamycin (doxorubicin)	Hodgkin's lymphoma
CHOP	Cyclophosphamide, hydroxydoxorubicin (doxorubicin), vincristine (Oncovin), prednisone	Non-Hodgkin lymphoma
CHOP-R or R-CHOP	CHOP + rituximab	B cell non-Hodgkin lymphoma
COP or CVP	Cyclophosphamide, Oncovin (vincristine), prednisone	Non-Hodgkin lymphoma in patients with history of cardiovascular disease
CMF	Cyclophosphamide, methotrexate, fluorouracil (5-FU)	Breast Cancer
COPP	Cyclophosphamide, Oncovin (vincristine), procarbazine, prednisone	Non-Hodgkin lymphoma
EC	Epirubicin, cyclophosphamide	Breast cancer
ECF	Epirubicin, cisplatin, fluorouracil (5-FU)	Gastric cancer and oesophageal cancer
FEC	Fluorouracil (5-FU), epirubicin, cyclophosphamide	Breast Cancer
FOLFOX	Fluorouracil (5-FU), leucovorin (folinic acid), oxaliplatin	Colorectal cancer
FOLFIRI	Fluorouracil (5-FU), leucovorin (folinic acid), irinotecan	Colorectal cancer
m-BACOD	Methotrexate, bleomycin, Adriamycin (doxorubicin), cyclophosphamide, Oncovin (vincristine), dexamethasone	Non-Hodgkin lymphoma
MACOP-B	Methotrexate, leucovorin (folinic acid), Adriamycin (doxorubicin), cyclophosphamide, Oncovin (vincristine), prednisone, bleomycin	Non-Hodgkin lymphoma
MOPP	Mechlorethamine, Oncovin (vincristine), procarbazine, prednisone	Hodgkin's lymphoma
PCV	Procarbazine, CCNU (lomustine), vincristine	Brain tumors
ProMACE-MOPP	Methotrexate, Adriamycin (doxorubicin), cyclophosphamide, etoposide + MOPP	Non-Hodgkin lymphoma
ProMACE-CytaBOM	Prednisone, doxorubicin (adriamycin), cyclophosphamide, etoposide, cytarabine, bleomycin, Oncovin (vincristine), methotrexate, leucovorin	Non-Hodgkin lymphoma
R-FCM	Rituximab, fludarabine, cyclophosphamide, mitoxantrone	B cell non-Hodgkin lymphoma
Stanford V	Doxorubicin, mechlorethamine, bleomycin, vinblastine, vincristine, etoposide, prednisone	Hodgkin's lymphoma
Thal/Dex	Thalidomide, dexamethasone	Multiple myeloma
VAD	Vincristine, Adriamycin (doxorubicin), dexamethasone	Multiple myeloma
VAPEC-B	Vincristine, Adriamycin (doxorubicin), prednisone, etoposide, cyclophosphamide, bleomycin	Hodgkin's lymphoma

[edit] See also

• Chemotherapy
• Treatment Guidelines
• National Comprehensive Cancer Network

[edit] External links

• Christie Hospital Patient Information
• Description of regimens

v • d • e Chemotherapeutic agents/Antineoplastic agents (L01) Alkylating and alkylating-like agents Nitrogen mustards: (Chlorambucil, Chlormethine, Cyclophosphamide, Ifosfamide, Melphalan, Bendamustine, Uramustine) Nitrosoureas:(Carmustine, Fotemustine, Lomustine, Streptozocin) Platinum (alkylating-like): (Carboplatin, Cisplatin, Oxaliplatin, Triplatin tetranitrate, Satraplatin) Alkyl sulfonates:(Busulfan, Treosulfan) Hydrazines:(Procarbazine, Dacarbazine, Temozolomide) Aziridines:(ThioTEPA) Antimetabolites Folic acid: (Aminopterin, Methotrexate, Pemetrexed, Raltitrexed). Purine:(Cladribine, Clofarabine, Fludarabine, Mercaptopurine, Pentostatin, Thioguanine) Pyrimidine:(Capecitabine, Cytarabine, Decitabine, Fluorouracil, Floxuridine, Gemcitabine) Spindle poison/mitotic inhibitor Taxane: (Docetaxel, Larotaxel, Paclitaxel). Vinca: (Vinblastine, Vincristine, Vindesine, Vinorelbine). Cytotoxic/antitumor antibiotics Anthracycline family: (Daunorubicin, Doxorubicin, Epirubicin, Idarubicin, Mitoxantrone, Pixantrone, Valrubicin) streptomyces (Actinomycin, Bleomycin, Mitomycin, Plicamycin) - Hydroxyurea Topoisomerase inhibitors Camptotheca: (Camptothecin, Topotecan, Irinotecan, Rubitecan), Podophyllum:(Etoposide, Teniposide) CI monoclonal antibodies Receptor tyrosine kinase (Cetuximab, Panitumumab, Trastuzumab) - CD20 (Rituximab, Tositumomab) - other (Alemtuzumab, Bevacizumab, Gemtuzumab) Photosensitizers Aminolevulinic acid, Methyl aminolevulinate, Porfimer sodium, Verteporfin Tyrosine kinase inhibitors Axitinib, Bosutinib, Cediranib, Dasatinib, Erlotinib, Gefitinib, Imatinib, Lapatinib, Lestaurtinib, Nilotinib, Semaxanib, Sorafenib, Sunitinib, Vandetanib Cyclin-dependent kinase inhibitor Seliciclib Other retinoids (Alitretinoin, Tretinoin), Fusion protein (Aflibercept) - Altretamine, Amsacrine, Anagrelide, Arsenic trioxide, Asparaginase (Pegaspargase), Bexarotene, Bortezomib, Celecoxib, Denileukin diftitox, Elesclomol, Estramustine, Irofulven, Ixabepilone, Masoprocol, Mitotane, Oblimersen, Testolactone, Tipifarnib, Trabectedin