2,5-Dimethoxy-4-ethylamphetamine
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| 2,5-Dimethoxy-4-ethylamphetamine | |
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| IUPAC name | 1-(2,5-Dimethoxy-4-ethylphenyl)propan-2-amine |
| Identifiers | |
| CAS number | [22004-32-6] |
| SMILES | COc1cc(CC)c(cc1CC(C)N)OC |
| Properties | |
| Molecular formula | C13H21NO2 |
| Molar mass | 223.32 g/mol |
| Melting point |
194-195 °C (hydrochloride) |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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DOET, HECATE, or 2,5-dimethoxy-4-ethylamphetamine is an analogue of DOM, and is the three-carbon chain homologue to 2C-E. It produces hallucinogenic, psychedelic, and entheogenic effects.
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[edit] Chemistry
DOET is in a class of compounds commonly known as substituted amphetamines; its full chemical name is 4-ethyl-2,5-dimethoxy-alpha-methylbenzeneethanamine, or 1-(2,5-dimethoxy-4-ethylphenyl)propan-2-amine. It has an active stereocenter and (R)-DOET is the more active enantiomer. DOET is an extremely rare compound and reports of its effects and toxicology in humans are sparse. However, like the more common 2,5-dimethoxy-amphetamine analogues DOB, DOI and DOM, it is a potent and long-acting psychedelic. Removal of the alpha-methyl moiety yields the 2-carbon analogue, commonly known as 2C-E, another psychedelic compound first synthesized by Dr. Alexander Shuglin.
[edit] Effects
DOET produces psychedelic and entheogenic effects that last up 14-20 hours. In his book PiHKAL (Phenethylamines i Have Known And Loved), Alexander Shulgin lists a dosage of DOET as being 2-7 mg orally, with 6-7mg being the dosage for full, desired effects.
[edit] Pharmacology
The mechanism that produces the hallucinogenic and entheogenic effects of DOET is thought to result from its action as an agonist at the 5-HT2A serotonin receptor.
[edit] Dangers
The toxicity of DOET is not known.
[edit] Legality
DOET is classified as a Schedule 1 substance in the United States, and is similarly controlled in other parts of the world. Internationally, DOET is a Schedule I drug under the Convention on Psychotropic Substances[1].
[edit] See also
[edit] References
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[edit] External links
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