DOTFM

From Wikipedia, the free encyclopedia

DOTFM
Systematic (IUPAC) name
1-(4-(trifluoromethyl)-2,5-dimethoxyphenyl)-2-aminopropane
Identifiers
CAS number  ?
ATC code  ?
PubChem 10400521
Chemical data
Formula C12H16F3NO2 
Mol. mass 263.255 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

DOTFM is an analogue of the phenethylamine derived hallucinogen DOB where the bromine atom has been replaced by a trifluoromethyl group. It was discovered in 1994 by a team at Purdue University.

DOTFM is the amphetamine homolog of the phenethylamine hallucinogen 2C-TFM and is around twice as potent as 2C-TFM in animal studies. It acts as a potent agonist for the 5HT2A and 5HT2C receptors. In drug-substitution experiments in rats, DOTFM fully substituted for LSD and was slightly more potent than DOI.[1] Anecdotal reports from human users suggest that DOTFM is a potent hallucinogen with an extremely long duration of action, similar to Br-DFLY.


[edit] References

  1. ^ Nichols DE, Frescas S, Marona-Lewicka D, Huang X, Roth BL, Gudelsky GA, Nash JF. 1-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: a potent serotonin 5-HT2A/2C agonist. Journal of Medicinal Chemistry. 1994 Dec 9;37(25):4346-51. PMID 7996545
Tablets  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.
v • d • e
Psychedelic phenethylamines

Aleph • 2C-B • 2C-B-FLY • 2C-C • 2C-D • 2C-E • 2C-F • 2C-G • 2C-I • 2C-N • 2C-O • 2C-O-4 • 2C-P • 2C-T • 2C-T-2 • 2C-T-4 • 2C-T-7 • 2C-T-8 • 2C-T-9 • 2C-T-13 • 2C-T-15 • 2C-T-17 • 2C-T-21 • 2C-TFM • 2C-YN • 25I-NBOH • 25I-NBOMe • 3C-E • 3C-P • Br-DFLY • DESOXY • DMMDA-2 • DOB • DOC • DOET • DOI • DOM • DON • DOPR • DOTFM • Escaline • Ganesha • HOT-2 • HOT-7 • HOT-17 • Isoproscaline • Lophophine • MDA • MMDA • MMDA-2 • MMDA-3a • MMDMA • Macromerine • Mescaline • Proscaline • TCB-2 • TMA