S-Adenosyl-L-homocysteine

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S-Adenosyl-L-homocysteine
Other names	AdoHcy, 2-S-adenosyl-L-homocysteine, S-adenosylhomocysteine, SAH
Identifiers
CAS number	[979-92-0]
PubChem	193
KEGG	C00021
MeSH	S-Adenosylhomocysteine
ChEBI	16680
SMILES	N[C@@H](CCSC[C@H]1O[C@H]([C@H](O) [C@@H]1O)N2C=NC3=C2N=CN=C3N)C(O)=O
Properties
Molecular formula	C14H20N6O5S
Molar mass	384.41 g mol-1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

S-Adenosyl-L-homocysteine is an amino acid derivative used in several metabolic pathways in the organism Escherichia coli. It is an intermediate in the synthesis of cysteine.

S-(5'-deoxy-5'-adenosyl)-l-homocysteine is a compound formed by the demethylation of S-adenosyl-L-methionine (SAM).

[edit] External links

• BioCYC E.Coli K-12 Compund: S-adenosyl-L-homocysteine

v • d • e Amino acid metabolism intermediates K→acetyl-CoA lysine→ Saccharopine - Allysine - Alpha-aminoadipate - Alpha-ketoadipic acid - Glutaryl-CoA - Glutaconyl-CoA - Crotonyl-CoA - Beta-hydroxybutyryl-CoA leucine→ Alpha-ketoisocaproic acid - Isovaleryl-CoA - 3-Methylcrotonyl-CoA - 3-Methylglutaconyl-CoA - HMG-CoA tryptophan→alanine→ N'-Formylkynurenine - Kynurenine - Anthranilic acid - 3-hydroxykynurenine - 3-Hydroxyanthranilic acid - 2-Amino-3-carboxymuconic semialdehyde - 2-aminomuconic semialdehyde - 2-Aminomuconic acid - Glutaryl-CoA G→glutamate histidine→ Urocanic acid - Imidazol-4-one-5-propionic acid - Formiminoglutamic acid - Glutamate-1-semialdehyde proline→ 1-Pyrroline-5-carboxylic acid arginine→ Ornithine - Putrescine - Agmatine G→propionyl-CoA methionine→ S-Adenosyl methionine - S-Adenosyl-L-homocysteine - Homocysteine - Cystathionine - alpha-Ketobutyric acid isoleucine→ 2,3-Dihydroxy-3-methylpentanoic acid - 2-Methylbutyryl-CoA - Tiglyl-CoA - 2-methylacetoacetyl-CoA valine→ Alpha-ketoisovalerate - Isobutyryl-CoA - Methacrylyl-CoA - 3-Hydroxyisobutyryl-CoA - 3-Hydroxyisobutyrate - 2-methyl-3-oxopropanoate threonine→ Alpha-ketobutyric acid propionyl-CoA→ Methylmalonyl-CoA G→fumarate phenylalanine→tyrosine→ 4-Hydroxyphenylpyruvic acid - Homogentisic acid - 4-Maleylacetoacetate Other cysteine+glutamate→glutathione gamma-Glutamylcysteine glycine→creatine Glycocyamine - Phosphocreatine - Creatinine Other Glycerate 3-phosphate (serine) - Cysteine sulfinic acid see also enzymes, disorders