Interleukin 32

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Interleukin 32
Identifiers
Symbol	IL32
Alt. Symbols	, NK4, TAIF, TAIFb, TAIFd
Entrez	9235
HUGO	16830
OMIM	606001
RefSeq	NM_004221
UniProt	P24001
Other data
Locus	Chr. 16 p13.3

Interleukin 32 (IL-32) is a cytokine that can induce cells of the immune system (such as monocytes and macrophages) to secrete tumor necrosis factor-alpha (TNF-α) in addition to chemokines such as IL-8 and MIP-2/CXCL2.^[1]

[edit] References

1. ^ Kim SH, Han SY, Azam T, Yoon DY, Dinarello CA. Interleukin-32: a cytokine and inducer of TNFalpha, Immunity, 2005, Volume 22, Issue 1, pages 131-42.

v • d • e Cytokines: interleukins IL-1 superfamily IL-1 (IL-1Ra) - IL-18 - IL-33 IL-6 like/gp130 utilizing IL-6 - IL-11 - IL-27 - IL-30 - IL-31 (+non IL Oncostatin M, Leukemia inhibitory factor, Ciliary neurotrophic factor, Cardiotrophin 1) IL-10 family IL-10 - IL-19 - IL-20 - IL-22 - IL-24 - IL-26 Interferon type III IL-28 - IL-29 Common γ-chain family IL-2/IL-15 - IL-3 - IL-4 - IL-7 - IL-9 - IL-13 - IL-21 IL-12 family IL-12 - IL-23 - IL-27 - IL-35 Other IL-5 - IL-8 - IL-14 - IL-16 - IL-17/IL-25 (A) - IL-32