Complement component 1s


The C1 protein, showing subunits C1r, C1s, and the C1q tails.
complement component 1, s subcomponent
Identifiers
Symbol	C1S
Entrez	716
HUGO	1247
OMIM	120580
RefSeq	NM_001734
UniProt	P09871
Other data
EC number	3.4.21.42
Locus	Chr. 12 p13

Complement component 1S is a protein involved in the complement system.

C1s cleaves C4, which eventually leads to the production of the C4b-C2a form of C3-convertase.

Classical pathway. (Some labels are in Polish.)

[edit] External links

This article on a gene on chromosome 12 is a stub. You can help Wikipedia by expanding it.

v • d • e Proteins: complement system (C, L, A)

Activators	CLA: C3-convertase - C5-convertase - MAC (C6, C7, C8, C9) - L: Mannan-binding lectin - A: Factor P/Properdin

Enzymes	C: C1Q/C1R/C1S - C4 (C4a) - C2 - CLA: C3 (C3a, C3b/iC3b) - C5 (C5a) - L: MASP1 - MASP2 - A: Complement factor B - Factor D

Inhibitors	CLA: C1-inhibitor - Decay accelerating factor - Factor I - CL: C4BP - A: Factor H

Complement receptors	CR1 - CR2 - CR3 - CR4 - CD11b/CD11c/CD18 - Anaphylatoxin (C3a, C5a)