Factor D

Factor D is a protein involved in the alternative complement pathway of the complement system.

It cleaves Factor B.

Alternative pathway. (Some labels are in Polish.)

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v • d • e Proteins: complement system (C, L, A)

Activators	CLA: C3-convertase - C5-convertase - MAC (C6, C7, C8, C9) - L: Mannan-binding lectin - A: Factor P/Properdin

Enzymes	C: C1Q/C1R/C1S - C4 (C4a) - C2 - CLA: C3 (C3a, C3b/iC3b) - C5 (C5a) - L: MASP1 - MASP2 - A: Complement factor B - Factor D

Inhibitors	CLA: C1-inhibitor - Decay accelerating factor - Factor I - CL: C4BP - A: Factor H

Complement receptors	CR1 - CR2 - CR3 - CR4 - CD11b/CD11c/CD18 - Anaphylatoxin (C3a, C5a)

v • d • e Endopeptidases: serine proteases/serine endopeptidases (EC 3.4.21)

Digestive enzymes	Enteropeptidase - Trypsin - Chymotrypsin - Elastase (Neutrophil, Pancreatic)

Coagulation	factors: Thrombin - Factor VIIa - Factor IXa - Factor Xa - Factor XIa - Factor XIIa - Kallikrein (PSA) fibrinolysis: Plasmin - Tissue plasminogen activator - Urinary plasminogen activator

Complement system	Factor B - Factor D - Factor I - MASP (MASP1, MASP2) - C3-convertase

Other immune system	Chymase - Granzyme - Tryptase - Proteinase 3/Myeloblastin

Venombin	Ancrod - Batroxobin

Other	Acrosin - Prolyl endopeptidase - Pronase - Proprotein convertases (1, 2) - Subtilisin/Furin - Streptokinase - S1P