From Wikipedia, the free encyclopedia
Alimemazine (INN), also known as trimeprazine (former BAN and USAN; trade names Nedeltran, Panectyl, Repeltin, Therafene, Theralen, Theralene, Vallergan, Vanectyl, or Temaril), commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine).[1] It also acts as a sedative and anti-emetic for prevention of motion sickness. Although it is structurally related to drugs such as chlorpromazine (Thorazine), it is not used as an anti-psychotic treatment.[2] It is no longer available in the United States.[3] The elimination half life is approximately 5 hours.[4]
[edit] References
- ^ PubChem CID 78032.
- ^ Drugbank:Trimeprazine.
- ^ MedlinePlus:Trimeprazine.
- ^ Hu OY; Gfeller E, Perrin JH, Curry SH (Mar 1986). "Relative bioavailability of trimeprazine tablets investigated in man using HPLC with electrochemical detection". J Pharm Pharmacol 38 (3): 172-6. PMID 2871150.
