Diphenylpyraline

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Diphenylpyraline
Systematic (IUPAC) name
4-benzhydryloxy-1-methyl-piperidine
Identifiers
CAS number 147-20-6
ATC code R06AA07
PubChem 3103
DrugBank APRD00719
Chemical data
Formula C19H23NO 
Mol. mass 281.392 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Diphenylpyraline is an antihistamine.

[edit] External links

  • Lapa G, Mathews T, Harp J, Budygin E, Jones S (2005). "Diphenylpyraline, a histamine H1 receptor antagonist, has psychostimulant properties". Eur J Pharmacol 506 (3): 237–40. doi:10.1016/j.ejphar.2004.11.017. PMID 15627433. 
  • Ohno T, Kobayashi S, Hayashi M, Sakurai M, Kanazawa I (2001). "Diphenylpyraline-responsive parkinsonism in cerebrotendinous xanthomatosis: long-term follow up of three patients". J Neurol Sci 182 (2): 95–7. doi:10.1016/S0022-510X(00)00441-X. PMID 11137513. 
  • Puhakka H, Rantanen T, Virolainen E (1977). "Diphenylpyraline (Lergobine) in the treatment of patients suffering from allergic and vasomotor rhinitis". J Int Med Res 5 (1): 37–41. PMID 14039. 
v • d • e
Antihistamines (primarily R06)
Aminoalkyl ethers
Substituted alkylamines
Substituted ethylenediamines
Phenothiazine derivatives
Piperazine derivatives
Others for systemic use
For topical use
Antiallergic agents excluding corticosteroids
Other antiallergics


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