Type-II collagen

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collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital)
Identifiers
Symbol COL2A1
Alt. Symbols SEDC
Entrez 1280
HUGO 2200
OMIM 120140
RefSeq NM_001844
UniProt P02458
Other data
Locus Chr. 12 q13.11-q13.2

Type-II collagen is the basis for articular cartilage and hyaline cartilage.

It makes up 50% of all protein in cartilage and 85-90% of collagen of articular cartilage.

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Type II collagen does form fibers. This fibrillar network of collagen allows cartilage to entrap the proteoglycan aggregate as well as provide tensile strength to the tissue.

[edit] External links