Rufinamide

From Wikipedia, the free encyclopedia

Rufinamide
Systematic (IUPAC) name
1-[(2,6-difluorophenyl)methyl]triazole-4-carboxamide
Identifiers
CAS number	106308-44-5
ATC code	N03AF03
PubChem	129228
Chemical data
Formula	C10H8F2N4O
Mol. mass	238.194
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Rufinamide is an anticonvulsant medication.

Used in combination with other medication and therapy to treat Lennox-Gastaut syndrome and various other seizure disorders, Rufinamide, a triazole derivative, was developed in 2004 by Novartis Pharma, AG, and is manufactured by Eisai.

[edit] References

• Drugs.com - Rufinamide
• Epilepsy.com - Rufinamide

v • d • e Anticonvulsants (N03) Barbiturates Barbexaclone, Metharbital, Methylphenobarbital, Pentobarbital, Phenobarbital, Primidone Hydantoins Ethotoin, Fosphenytoin, Mephenytoin, Phenytoin Oxazolidinediones Ethadione, Paramethadione, Trimethadione Succinimides Ethosuximide, Mesuximide, Phensuximide Benzodiazepines Clobazam, Clonazepam, Clorazepate, Diazepam, Lorazepam, Midazolam, Nimetazepam, Nitrazepam, Temazepam Carboxamides Carbamazepine, Oxcarbazepine, Rufinamide Fatty acid derivatives Valpromide, Valnoctamide Carboxylic acids Valproic acid (Sodium valproate & Valproate semisodium), Tiagabine Others GABA analogs: Gabapentin, Pregabalin, Progabide, Vigabatrin -- Monosaccharides: Topiramate -- Aromatic allylic alcohols: Stiripentol -- Ureas: Phenacemide, Pheneturide -- Phenyltriazines: Lamotrigine Carbamates: Emylcamate, Felbamate, Meprobamate -- Pyrrolidines: Brivaracetam, Levetiracetam, Nefiracetam, Seletracetam Sulfa drugs: Acetazolamide, Ethoxzolamide, Sultiame, Zonisamide -- Propionates: Beclamide -- Aldehydes: Paraldehyde -- Bromides: Potassium bromide, Sodium bromide