Mesuximide

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Mesuximide
Systematic (IUPAC) name
1,3-dimethyl-3-phenyl-pyrrolidine-2,5-dione
Identifiers
CAS number	77-41-8
ATC code	N03AD03
PubChem	6476
Chemical data
Formula	C₁₂H₁₃N O₂
Mol. mass	203.237 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	Hepatic (demethylation and glucuronidation)
Half life	1.4–2.6 hours (mesuximide) 28–38 hours (active metabolite)
Excretion	Renal
Therapeutic considerations
Pregnancy cat.	C(US)
Legal status	℞-only(US)
Routes	Oral

Mesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the tradenames Petinutin (Switzerland)^[1] and Celontin (United States).^[2]

[edit] References

^ Pfizer AG (2005). Petinutin (Mésuximide) (French). Official Pfizer AG Website. Retrieved on August 21, 2006.
^ Pfizer Inc. (2008). Celontin (methsuximide capsules, USP). Official Pfizer Inc. Website. Retrieved on June 10, 2008.

v • d • e Anticonvulsants (N03)

Barbiturates	Barbexaclone, Metharbital, Methylphenobarbital, Pentobarbital, Phenobarbital, Primidone

Hydantoins	Ethotoin, Fosphenytoin, Mephenytoin, Phenytoin

Oxazolidinediones	Ethadione, Paramethadione, Trimethadione

Succinimides	Ethosuximide, Mesuximide, Phensuximide

Benzodiazepines	Clobazam, Clonazepam, Clorazepate, Diazepam, Lorazepam, Midazolam, Nimetazepam, Nitrazepam, Temazepam

Carboxamides	Carbamazepine, Oxcarbazepine, Rufinamide

Fatty acid derivatives	Valpromide, Valnoctamide

Carboxylic acids	Valproic acid (Sodium valproate & Valproate semisodium), Tiagabine

Others	GABA analogs: Gabapentin, Pregabalin, Progabide, Vigabatrin -- Monosaccharides: Topiramate -- Aromatic allylic alcohols: Stiripentol -- Ureas: Phenacemide, Pheneturide -- Phenyltriazines: Lamotrigine Carbamates: Emylcamate, Felbamate, Meprobamate -- Pyrrolidines: Brivaracetam, Levetiracetam, Nefiracetam, Seletracetam Sulfa drugs: Acetazolamide, Ethoxzolamide, Sultiame, Zonisamide -- Propionates: Beclamide -- Aldehydes: Paraldehyde -- Bromides: Potassium bromide, Sodium bromide