Paramethadione

From Wikipedia, the free encyclopedia

Paramethadione
Systematic (IUPAC) name
5-ethyl-3,5-dimethyl-oxazolidine-2,4-dione
Identifiers
CAS number	115-67-3
ATC code	N03AC01
PubChem	8280
DrugBank	APRD00236
Chemical data
Formula	C7H11NO3
Mol. mass	157.167 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	Not significant
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	D(US)
Legal status
Routes	?

Paramethadione is an anticonvulsant in the oxazolidinedione class. It is associated with fetal trimethadione syndrome, which is also known as paramethadione syndrome.^[1]

[edit] References

[edit] External links

• DDB 33106
• Hoffman, D; Chun A (1975). "Paramethadione and metabolite serum levels in humans after a single oral paramethadione dose". J Pharm Sci 64 (10): 1702–1703. doi:10.1002/jps.2600641027. PMID 1185541. 

v • d • e Anticonvulsants (N03) Barbiturates Barbexaclone, Metharbital, Methylphenobarbital, Pentobarbital, Phenobarbital, Primidone Hydantoins Ethotoin, Fosphenytoin, Mephenytoin, Phenytoin Oxazolidinediones Ethadione, Paramethadione, Trimethadione Succinimides Ethosuximide, Mesuximide, Phensuximide Benzodiazepines Clobazam, Clonazepam, Clorazepate, Diazepam, Lorazepam, Midazolam, Nimetazepam, Nitrazepam, Temazepam Carboxamides Carbamazepine, Oxcarbazepine, Rufinamide Fatty acid derivatives Valpromide, Valnoctamide Carboxylic acids Valproic acid (Sodium valproate & Valproate semisodium), Tiagabine Others GABA analogs: Gabapentin, Pregabalin, Progabide, Vigabatrin -- Monosaccharides: Topiramate -- Aromatic allylic alcohols: Stiripentol -- Ureas: Phenacemide, Pheneturide -- Phenyltriazines: Lamotrigine Carbamates: Emylcamate, Felbamate, Meprobamate -- Pyrrolidines: Brivaracetam, Levetiracetam, Nefiracetam, Seletracetam Sulfa drugs: Acetazolamide, Ethoxzolamide, Sultiame, Zonisamide -- Propionates: Beclamide -- Aldehydes: Paraldehyde -- Bromides: Potassium bromide, Sodium bromide