Prolactin receptor
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prolactin receptor
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| Identifiers | |
| Symbol | PRLR |
| Entrez | 5618 |
| HUGO | 9446 |
| OMIM | 176761 |
| RefSeq | NM_000949 |
| UniProt | P16471 |
| Other data | |
| Locus | Chr. 5 p13-p12 |
The prolactin receptor—encoded by a gene on Chromosome 5p13-14—interacts with the prolactin molecule as a transmembrane receptor.
Thus it contains an extracellular region that binds prolactin, a transmembrane regions, and a cytoplasmatic region.
The receptor is a cytokine receptor, and the second messenger cascade is the JAK-STAT pathway.
There may be variations among different tissue prolactin receptors.
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