Pinosylvin synthase

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In enzymology, a pinosylvin synthase (EC 2.3.1.146) is an enzyme that catalyzes the chemical reaction

3 malonyl-CoA + cinnamoyl-CoA 4 CoA + pinosylvin + 4 CO₂

Thus, the two substrates of this enzyme are malonyl-CoA and cinnamoyl-CoA, whereas its 3 products are CoA, pinosylvin, and CO₂.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing). Other names in common use include stilbene synthase, and pine stilbene synthase. This enzyme participates in phenylpropanoid biosynthesis.

[edit] References

• IUBMB entry for 2.3.1.146
• BRENDA references for 2.3.1.146 (Recommended.)
• PubMed references for 2.3.1.146
• PubMed Central references for 2.3.1.146
• Google Scholar references for 2.3.1.146
• Gehlert R, Schoppner A and Kindl H (1990). "Stilbene synthase from seedlings of Pinus sylvestris - purification and induction in response to fungal infection". Mol. Plant-Microbe Interaction 3: 444–449. 

[edit] External links

The CAS registry number for this enzyme class is 72994-49-1.

• IUBMB entry for 2.3.1.146

• KEGG entry for 2.3.1.146

• BRENDA entry for 2.3.1.146

• NiceZyme view of 2.3.1.146

• EC2PDB: PDB structures for 2.3.1.146

• PRIAM entry for 2.3.1.146

• PUMA2 entry for 2.3.1.146

• IntEnz: Integrated Enzyme entry for 2.3.1.146

• MetaCyc entry for 2.3.1.146

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050198: pinosylvin synthase

• AMIGO entry for GO code 0050198: pinosylvin synthase