Nexin

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Nexin can be located on this cross-section of an axoneme
Nexin can be located on this cross-section of an axoneme

Nexin is a protein that prevents microtubules in the outer layer of axonemes from movement with respect to each other. Otherwise vesicular transport proteins such as dynein would dissolve the whole structure.[1]

[edit] Sorting nexin

Sorting nexins are a large group of proteins with the common characteristic of having a PX domain (a phospholipid-binding motif).[2]

Such nexins are transcribed from the following genes: SNX1, SNX2, SNX3, SNX4, SNX5, SNX6, SNX7, SNX8, SNX9, SNX10, SNX11, SNX12, SNX13, SNX14, SNX15, SNX16, SNX17... SNX26, SNX27

[edit] References

  1. ^ Walter F., PhD. Boron (2003). Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders, 1300. ISBN 1-4160-2328-3.  Page 26
  2. ^ Worby CA, Dixon JE (2002). "Sorting out the cellular functions of sorting nexins". Nat. Rev. Mol. Cell Biol. 3 (12): 919–31. doi:10.1038/nrm974. PMID 12461558.