Talk:Metabolic syndrome
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[edit] I
I am very much inclined to move this article to metabolic syndrome, which seems to be accepted nomenclature (see J Clin Endocrinol Metab of June 2004). Any views or comments?? JFW | T@lk 10:47, 8 Jun 2004 (UTC)
Agree. Current nomenclature is metabolic syndrome. Maintain redirect, of course. Kd4ttc 02:37, 9 Jun 2004 (UTC)
note that on your section with regards to diagnostic criteria - you include six criteria , not five. i wasn't aware that an elevated CRP was one of the criteria. alex tan. 62.6.139.10 (talk · contribs)
- You are completely right. I have no idea who inserted that. Thanks. JFW | T@lk 12:51, 31 October 2005 (UTC)
I agree with your observation on this .I also beleive that given the fact the patient with metabolic syndrome have high incidence of cardiovascular disease.It would be even prudent to call it cardiometabolic syndrome as some of the recent leading researched in this field having been doing.
- I have not heard the term "cardiometabolic syndrome". It may not be notable enough to be mentioned in the article. JFW | T@lk 20:34, 14 February 2006 (UTC)
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- Heh. It was coined by Sanofi-Aventis to push rimonabant. I hear it in active use all the time now :-). JFW | T@lk 12:47, 12 May 2008 (UTC)
[edit] War is over
Apparently the AHA and ADA differed in how the metabolic syndrome should be addressed. They have now agreed on some things. Do we include this?[1]. JFW | T@lk 10:42, 21 August 2006 (UTC)
don't think the war is completely over - at the 2006 ADA conference, alberti and kahn were presenting arguments for the different diagnostic criteria for the syndrome (WHO/IDF vs ADA/EASD). there were also comments about whether it was necessary at all to have the metabolic syndrome label... identify CVS risk factors individually and treat accordingly.
[edit] Dysmetabolic syndrome
I don't understand why it is called "metabolic" syndrome when it really is a dysmetabolic syndrome. Everyone has a metabolic syndrome: well, everyone that's living that is. I know it is overwhelmingly standard to not use the dys- prefix, but are there any sources arguing my point that "metabolic syndrome" is misnamed? Practically every medical term I can think of relies on proper use of suffixes, prefixes, and root words (see List of medical roots) and this seems to go against that. Sloppy terminology, if you will. Cburnett 04:36, 7 December 2006 (UTC)
- I don't have much experience at Wikipedia, but it seems to me that an encyclopedia should be DEscriptive, not PREscriptive. That is, Wikipedia should not tell the medical community what terminology SHOULD BE used, but should report using the terminology that IS used.Rocky143 05:17, 4 January 2007 (UTC)
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- I thought I made it pretty clear; I repeat:
- ...are there any sources arguing my point that "metabolic syndrome" is misnamed?
- I am NOT saying wikipedia should dictate. I am stating that I think it's wrong and I am ASKING if any one knows of any sources regarding it being misnamed. If dysmetabolic syndrome can be sourced then WP is not dictating, it's reporting. Cburnett 05:50, 4 January 2007 (UTC)
- I thought I made it pretty clear; I repeat:
[edit] mmol/L and mg/dL
Someone who knows how should supply mg/dL figures to supplement the mmol/L figures in this article.Rocky143 05:18, 4 January 2007 (UTC)
[edit] Metformin
The article about treatment is misleading, it says that the treatment of insulin resistance by Metformin is not FDA approved, but if you go to the article on Metformin it says that it is FDA approved. So which is it?
--> Metformin is approved for treatment of type 2 diabetes, not metabolic syndrome —Preceding unsigned comment added by 68.45.246.66 (talk) 12:53, 1 September 2007 (UTC)
[edit] I changed some stuff.
I removed the symptoms in the first section because they were duplicated in the diagnosis section. I also added the citation for Grundy. Rhetth 00:20, 14 July 2007 (UTC)
[edit] Elevated CRP and TNF-alpha
I have read in some sources that indeed these are elevated in metabolic syndrome. Can anyone with greater knowledge confirm this? Russthomas15 07:13, 14 November 2007 (UTC)
- hsCRP is a marker not of metabolic syndrome but probably atherosclerotic burden. In a patient with MetS who also has a high CRP (and no evidence of infection or autoimmune disease) there is good reason to be a bit nervous.
- TNFα is secreted by monocytes that have populated adipose tissue. It is a marker of obesity, again in patients who have other confounding conditions. It is not measured routinely and probably of limited clinical relevance. Interestingly, patients who receive infliximab (a TNF inhibitor) tend to get better glycaemic control when diabetic, suggesting that TNF does play a role in insulin resistance. JFW | T@lk 12:51, 12 May 2008 (UTC)
[edit] Added
This reference was left on the userpage:
- Ford ES, Giles WH, Dietz WH: Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 287:356–359, 2002
It looks useful, but it had no content associated with it. JFW | T@lk 21:16, 16 January 2008 (UTC)
I put this reference back in with a link to the PubMed article. Dcwebb (talk) 16:09, 21 May 2008 (UTC)
[edit] Ouch
In the Cardiovascular Health Study, diagnosis of metabolic syndrome by either WHO or IDF criteria made little difference in mortality compared to simply diagnosing and treating hypertension and elevated fasting glucose (EFG). Food for thought, and probably part of a trend against the use of metabolic syndrome as a bona fide diagnosis. JFW | T@lk 12:45, 12 May 2008 (UTC)
